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Implanon and Advil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Implanon (etonogestrel) and Advil (ibuprofen). Common drug interactions include breech presentation among females.

The phase IV clinical study analyzes what interactions people have when they take Implanon and Advil. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Implanon?

Implanon has active ingredients of etonogestrel. It is often used in birth control. eHealthMe is studying from 12,479 Implanon users. Check the latest studies of Implanon.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,534 Advil users. Check the latest studies of Advil.

On Aug, 11, 2026

19 people who take Implanon and Advil together, and have interactions are studied.

Implanon and Advil drug interactions.

What are the common drug interactions of Implanon and Advil, by gender? *:

female:

  1. Breech presentation
  2. Drug ineffective
  3. Abdominal discomfort
  4. Anxiety
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Device dislocation
  7. Dizziness
  8. Drug exposure during pregnancy
  9. Dry eye (lack of adequate tears)
  10. Eye pruritus (eye itching)

male:

n/a

What are the common drug interactions of Implanon and Advil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  2. Ear infection
  3. Metrorrhagia (uterine bleeding at irregular intervals)
  4. Haemorrhage (bleeding)

20-29:

  1. Device dislocation
  2. Dizziness
  3. General physical health deterioration (weak health status)
  4. Injury
  5. Nausea (feeling of having an urge to vomit)
  6. Pain in extremity
  7. Pelvic adhesions
  8. Pelvic pain
  9. Uterine perforation (accidental puncture of the uterus)
  10. Abdominal pain lower

30-39:

  1. Implant site cellulitis (skin infection at implant site)

40-49:

  1. Breech presentation
  2. Pregnancy with implant contraceptive
  3. Drug ineffective
  4. Unwanted pregnancy
  5. Drug exposure during pregnancy
  6. Uterine disorder

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 31.58%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 26.32%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.53%
  4. Migraine (headache): 2 people, 10.53%
  5. Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.26%
  6. Menstrual Disorder (disease of menstrual cycle): 1 person, 5.26%
  7. Hypersensitivity: 1 person, 5.26%
  8. Genital Herpes (herpes infection of genital): 1 person, 5.26%
  9. Dysmenorrhea (painful menstruation): 1 person, 5.26%
  10. Depression: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Implanon and Advil?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Implanon and Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Implanon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Implanon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Advil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on etonogestrel and ibuprofen (the active ingredients of Implanon and Advil, respectively), and Implanon and Advil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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