Imuran and Neupogen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imuran (azathioprine) and Neupogen (filgrastim). Common drug interactions include nasal ulcer among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Imuran and Neupogen. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Imuran?

Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

40 people who take Imuran and Neupogen together, and have interactions are studied.

What are the common drug interactions of Imuran and Neupogen, by gender? *:

female:

Nasal ulcer (ulcer of nose)
Nausea (feeling of having an urge to vomit)
Osteitis (a general term for inflammation of bone)
Palpitations (feelings or sensations that your heart is pounding or racing)
Peripheral swelling
Psoriasis (immune-mediated disease that affects the skin)
Vaginal haemorrhage (vaginal bleeding)
Vomiting
Abdominal distension
Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)

male:

Abdominal pain upper
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Rash erythematous (redness of the skin)
Rectal haemorrhage (bleeding from anus)
Lung neoplasm malignant (cancer tumour of lung)
Fall
Nasopharyngitis (inflammation of the nasopharynx)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the common drug interactions of Imuran and Neupogen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pyrexia (fever)
Acute sinusitis
Anaemia (lack of blood)
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic valve incompetence
Aortic valve sclerosis (narrowing of the aortic valve)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)

20-29:

Abdominal pain upper
Alanine aminotransferase increased
Aspartate aminotransferase increased
Bk virus infection
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Cerebral aspergillosis (pus collection with swelling in brain)
Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cytomegalovirus antigen positive
Diarrhoea

30-39:

Ageusia (loss of taste functions of the tongue)
Dysgeusia (disorder of the sense of taste)

40-49:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
Arthralgia (joint pain)
Asthma
Back pain
Contusion (a type of hematoma of tissue in which capillaries)
Decreased immune responsiveness
Fatigue (feeling of tiredness)

50-59:

Rash
Rash erythematous (redness of the skin)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Respiratory tract infection
Sinusitis (inflammation of sinus)
Spinal osteoarthritis (joint cartilage loss in spine)
Arthralgia (joint pain)
Asthma
Back pain
Contusion (a type of hematoma of tissue in which capillaries)

60+:

Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Rash erythematous (redness of the skin)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Nasopharyngitis (inflammation of the nasopharynx)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 10.00%
Anaemia (lack of blood): 4 people, 10.00%
Rickets (softening of bones): 3 people, 7.50%
Leukopenia (less number of white blood cells in blood): 3 people, 7.50%
Indigestion: 3 people, 7.50%
Gout (uric acid crystals building up in the body): 3 people, 7.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.50%
Depression: 3 people, 7.50%
Calcium Deficiency (lack of calcium): 3 people, 7.50%
Acute Kidney Failure: 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

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