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Imuran and Nexplanon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imuran (azathioprine) and Nexplanon (etonogestrel). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Imuran and Nexplanon. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Imuran?

Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.

What is Nexplanon?

Nexplanon has active ingredients of etonogestrel. It is often used in birth control. eHealthMe is studying from 46,431 Nexplanon users. Check the latest studies of Nexplanon.

On Jul, 13, 2026

22 people who take Imuran and Nexplanon together, and have interactions are studied.

Imuran and Nexplanon drug interactions.

What are the common drug interactions of Imuran and Nexplanon, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Pain
  3. Bladder hypertrophy (bladder overgrowth- increase in cell size)
  4. Cardiac failure
  5. Diarrhoea
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Injection site discomfort
  8. Injection site pain
  9. Renal cyst (kidney cyst)
  10. Spinal pain (pain in spine)

male:

n/a

What are the common drug interactions of Imuran and Nexplanon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  2. Cardiac failure
  3. Death
  4. Dyspnoea (difficult or laboured respiration)
  5. Hepatic failure (liver failure)
  6. Pain
  7. Renal failure (kidney dysfunction)
  8. Swelling

50-59:

  1. Fatigue (feeling of tiredness)
  2. Headache (pain in head)
  3. Diarrhoea
  4. Renal cyst (kidney cyst)
  5. Spinal pain (pain in spine)
  6. Blood pressure increased
  7. Cataract (clouding of the lens inside the eye)
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Ear infection
  10. Fall

60+:

n/a

What are the existing conditions these people have? *

  1. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 11 people, 50.00%
  2. Immunodeficiency Common Variable: 4 people, 18.18%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Imuran and Nexplanon?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Imuran and Nexplanon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imuran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nexplanon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imuran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nexplanon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on azathioprine and etonogestrel (the active ingredients of Imuran and Nexplanon, respectively), and Imuran and Nexplanon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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