Indocin and Propulsid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Indocin (indomethacin) and Propulsid (cisapride monohydrate). Common drug interactions include asthma among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Indocin and Propulsid. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Indocin?

Indocin has active ingredients of indomethacin. It is often used in gout. eHealthMe is studying from 4,559 Indocin users. Check the latest studies of Indocin.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 05, 2026

19 people who take Indocin and Propulsid together, and have interactions are studied.

Indocin and Propulsid drug interactions.

What are the common drug interactions of Indocin and Propulsid, by gender? *:

female:

  1. Asthma
  2. Blood cholesterol increased
  3. Cough
  4. Depressed level of consciousness
  5. Dyspepsia (indigestion)
  6. Electrocardiogram abnormal
  7. Electrocardiogram qt corrected interval prolonged
  8. Fungal infection
  9. Hypertension (high blood pressure)
  10. Hypokalaemia (low potassium)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Adult respiratory distress syndrome (type of lung (pulmonary) failure)
  3. Headache (pain in head)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  7. Nausea (feeling of having an urge to vomit)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Pain in extremity
  10. Pulmonary vasculitis

What are the common drug interactions of Indocin and Propulsid, by age (0-1 to 60+)? *:

0-1:

  1. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  2. Infection

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Migraine (headache)
  4. Mitral valve replacement
  5. Oedema (fluid collection in tissue)
  6. Oxygen saturation decreased
  7. Pleurisy (inflammation of the pleurae, which causes pain when breathing)
  8. Polyp
  9. Postural hypotension
  10. Rales (an abnormal respiratory sound characterized by fine crackles)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Adult respiratory distress syndrome (type of lung (pulmonary) failure)
  3. Headache (pain in head)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  7. Nausea (feeling of having an urge to vomit)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Pain in extremity
  10. Pulmonary vasculitis

What are the existing conditions these people have? *

  1. Migraine (headache): 2 people, 10.53%
  2. Joint Pain: 2 people, 10.53%
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Indocin and Propulsid?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Indocin and Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Indocin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Indocin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Propulsid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on indomethacin and cisapride monohydrate (the active ingredients of Indocin and Propulsid, respectively), and Indocin and Propulsid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: