Indomethacin and Compazine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Indomethacin (indomethacin) and Compazine (prochlorperazine maleate). Common drug interactions include vertigo among females and headache among males.
The phase IV clinical study analyzes what interactions people have when they take Indomethacin and Compazine. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Indomethacin?
Indomethacin has active ingredients of indomethacin. It is often used in gout. eHealthMe is studying from 16,884 Indomethacin users. Check the latest studies of Indomethacin.
What is Compazine?
Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.
32 people who take Indomethacin and Compazine together, and have interactions are studied.

What are the common drug interactions of Indomethacin and Compazine, by gender? *:
female:
- Vertigo
- Alopecia (absence of hair from areas of the body)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Asthenia (weakness)
- Balance disorder
- Decreased appetite
- Diarrhoea
- Dizziness
- Dysphagia (a condition in which swallowing is difficult or painful)
- Fall
male:
- Headache (pain in head)
- Anxiety
- Basal ganglion degeneration (loss of brain tissue in the cortex, or outer layer of the brain)
- Carotid arteriosclerosis (plaque deposition in artery)
- Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
- Cerebral small vessel ischaemic disease (inadequate blood supply to small blood vessel of brain)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Confusional state
- Diarrhoea
- Disturbance in attention
What are the common drug interactions of Indomethacin and Compazine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain
- Anxiety
- Depression
- Diarrhoea
30-39:
- Abdominal pain upper
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
- Pain
- Vertigo
40-49:
- Social problem
- Spinal osteoarthritis (joint cartilage loss in spine)
- Suicidal ideation
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Chronic kidney disease
- Decreased appetite
- Diarrhoea
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Rash pruritic (redness with itching)
50-59:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anxiety
- Back pain
- Chills (felling of cold)
- Constipation
- Depression
- Dizziness
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Fatigue (feeling of tiredness)
- General symptom
60+:
- Alopecia (absence of hair from areas of the body)
- Asthenia (weakness)
- Hypertension (high blood pressure)
- Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
- Oedema peripheral (superficial swelling)
- Oral pain
- Oropharyngeal pain
- Weight decreased
- Hyperbilirubinaemia (excess of bilirubin in the blood)
- Jaundice cholestatic
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 10 people, 31.25%
- Pain: 6 people, 18.75%
- High Blood Pressure: 5 people, 15.62%
- Migraine (headache): 5 people, 15.62%
- Cystic Fibrosis (disease of the secretary glands): 4 people, 12.50%
- Stress And Anxiety: 4 people, 12.50%
- Headache (pain in head): 4 people, 12.50%
- Constipation: 3 people, 9.38%
- Insomnia (sleeplessness): 3 people, 9.38%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.38%
* Approximation only. Some reports may have incomplete information.
Do you take Indomethacin and Compazine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Indomethacin (16,884 reports)
- Compazine (13,646 reports)
Browse all drug interactions of Indomethacin and Compazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Indomethacin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Compazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Indomethacin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Compazine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mantarro S, Tuccori M, Pasqualetti G, Tognini S, Montagnani S, Monzani F, Blandizzi C, "Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient", BMC geriatrics, 2012 Nov .
- Mantarro S, Tuccori M, Pasqualetti G, Tognini S, Montagnani S, Monzani F, Blandizzi C, "Acute portal vein thrombosis precipitated by indomethacin in a HCV-positive elderly patient", BMC geriatrics, 2012 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on indomethacin and prochlorperazine maleate (the active ingredients of Indomethacin and Compazine, respectively), and Indomethacin and Compazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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