Infumorph and Clonidine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Infumorph (morphine sulfate) and Clonidine (clonidine). Common drug interactions include suicidal ideation among females and drug withdrawal syndrome among males.
The phase IV clinical study analyzes what interactions people have when they take Infumorph and Clonidine. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.
What is Infumorph?
Infumorph has active ingredients of morphine sulfate. eHealthMe is studying from 1,009 Infumorph users. Check the latest studies of Infumorph.
What is Clonidine?
Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.
43 people who take Infumorph and Clonidine together, and have interactions are studied.

What are the common drug interactions of Infumorph and Clonidine, by gender? *:
female:
- Suicidal ideation
- Pain
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
- Nausea (feeling of having an urge to vomit)
- Hyperhidrosis (abnormally increased sweating)
- Spinal cord disorder (disease of spinal cord)
- Device dislocation
- Implant site reaction
- Peripheral swelling
- Tenderness (pain or discomfort when an affected area is touched)
male:
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Overdose
- Back pain
- Blood pressure decreased
- Cough
- Death
- Excoriation (to tear or wear off the skin of)
- Fall
- Hypophagia (reduced food intake)
- Lumbosacral root pain
What are the common drug interactions of Infumorph and Clonidine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Mass
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Spinal cord disorder (disease of spinal cord)
- Back pain
- Lumbosacral root pain
40-49:
- Agitation (state of anxiety or nervous excitement)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Delusion (a false belief or opinion)
- Diplegia (paralysis of corresponding parts on both sides of the body)
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Granuloma (a small area of inflammation due to tissue injury)
- Hallucination (an experience involving the perception of something not present)
- Hip fracture
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
- Speech disorder
50-59:
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Activities of daily living impaired
- Device dislocation
- Device failure
- Dizziness
- Drug effect decreased
- Drug ineffective
- Headache (pain in head)
- Hypoaesthesia (reduced sense of touch or sensation)
- Implant site infection
60+:
- Overdose
- Confusional state
- Fall
- Granuloma (a small area of inflammation due to tissue injury)
- Hypophagia (reduced food intake)
- Implant site reaction
- Memory impairment
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Renal failure acute (rapid kidney dysfunction)
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
What are the existing conditions these people have? *
- Pain: 9 people, 20.93%
- Post Laminectomy Syndrome: 6 people, 13.95%
- Spinal Pain (pain in spine): 5 people, 11.63%
* Approximation only. Some reports may have incomplete information.
Do you take Infumorph and Clonidine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Infumorph and Clonidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Infumorph:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clonidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Infumorph and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonidine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on morphine sulfate and clonidine (the active ingredients of Infumorph and Clonidine, respectively), and Infumorph and Clonidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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