Injectafer and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Injectafer (ferric carboxymaltose) and Metformin (metformin hydrochloride). Common drug interactions include hypersensitivity among females and gout among males.

The phase IV clinical study analyzes what interactions people have when they take Injectafer and Metformin. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Injectafer?

Injectafer has active ingredients of ferric carboxymaltose. eHealthMe is studying from 3,270 Injectafer users. Check the latest studies of Injectafer.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,358 Metformin users. Check the latest studies of Metformin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

44 people who take Injectafer and Metformin together, and have interactions are studied.

Injectafer and Metformin drug interactions.

What are the common drug interactions of Injectafer and Metformin, by gender? *:

female:

Hypersensitivity
Loss of consciousness
Lymphocyte count decreased
Myalgia (muscle pain)
Neutrophil percentage increased
Overdose
Peripheral swelling
Protein total decreased
Nausea (feeling of having an urge to vomit)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)

male:

Gout (uric acid crystals building up in the body)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Respiratory tract infection
Thrombocytopenia (decrease of platelets in blood)
Vomiting
Diarrhoea

What are the common drug interactions of Injectafer and Metformin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Nausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chest pain
Emotional distress
Heart rate irregular
Hypertension (high blood pressure)

50-59:

Protein total decreased
Syncope (loss of consciousness with an inability to maintain postural tone)
Abdominal distension
Abdominal pain
Alopecia (absence of hair from areas of the body)
Blood glucose increased
Body temperature increased
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Dehydration (dryness resulting from the removal of water)
Diarrhoea

60+:

Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Nausea (feeling of having an urge to vomit)
Gait disturbance
Headache (pain in head)
Lung neoplasm malignant (cancer tumour of lung)
Oedema (fluid collection in tissue)
Pneumonia
Second primary malignancy (after getting cure a cancer, a new cancer development)
Thoracic vertebral fracture
Vomiting

What are the existing conditions these people have? *

Iron Deficiency Anaemia: 10 people, 22.73%
Anaemia (lack of blood): 6 people, 13.64%
Multiple Myeloma (cancer of the plasma cells): 5 people, 11.36%
High Blood Pressure: 5 people, 11.36%
Pain: 3 people, 6.82%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 3 people, 6.82%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 6.82%
Depression: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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