Inspra and Atarax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Inspra (eplerenone) and Atarax (hydroxyzine hydrochloride). Common drug interactions include body mass index increased among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Inspra and Atarax. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Inspra?

Inspra has active ingredients of eplerenone. It is often used in high blood pressure. eHealthMe is studying from 3,510 Inspra users. Check the latest studies of Inspra.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

On Aug, 11, 2026

26 people who take Inspra and Atarax together, and have interactions are studied.

What are the common drug interactions of Inspra and Atarax, by gender? *:

female:

Body mass index increased
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Thrombocytopenia (decrease of platelets in blood)
Vomiting
Weight increased
Hyperthyroidism (over activity of the thyroid gland)
Hypoxia (low oxygen in tissues)

male:

Dehydration (dryness resulting from the removal of water)
Cardiac failure
Oxygen saturation decreased
Pain
Pain in jaw
Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal failure (kidney dysfunction)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)
Cardiac failure congestive

What are the common drug interactions of Inspra and Atarax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Decreased appetite
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Thrombocytopenia (decrease of platelets in blood)
Vomiting
Weight increased

40-49:

n/a

50-59:

Dehydration (dryness resulting from the removal of water)
Body mass index increased
Abdominal pain
Cardiac failure congestive
Cholecystitis acute (rapid infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Diarrhoea
Fluid overload (too much fluid in the blood)
Tracheitis (an inflammation of the trachea)
Chronic kidney disease

60+:

Cardiac failure
Dyspnoea (difficult or laboured respiration)
Pain
Pain in jaw
Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal failure (kidney dysfunction)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)
Cough
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 30.77%
Nausea (feeling of having an urge to vomit): 5 people, 19.23%
Nausea And Vomiting: 5 people, 19.23%
Cardiac Failure: 4 people, 15.38%
Chronic Kidney Disease: 4 people, 15.38%
Gout (uric acid crystals building up in the body): 4 people, 15.38%
Headache (pain in head): 4 people, 15.38%
Itching: 4 people, 15.38%
Migraine (headache): 4 people, 15.38%
Wheezing (a high-pitched whistling sound made while you breath): 4 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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