Insulin and Demerol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Insulin (insulin pork) and Demerol (meperidine hydrochloride). Common drug interactions include lower respiratory tract infection among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Insulin and Demerol. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Insulin?

Insulin has active ingredients of insulin pork. It is often used in diabetes. eHealthMe is studying from 50,203 Insulin users. Check the latest studies of Insulin.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 12,706 Demerol users. Check the latest studies of Demerol.

On Jul, 13, 2026

49 people who take Insulin and Demerol together, and have interactions are studied.

What are the common drug interactions of Insulin and Demerol, by gender? *:

female:

Lower respiratory tract infection
Nerve compression
Pain in extremity
Blood pressure decreased
Oxygen saturation decreased
Blood pressure increased
Blood pressure fluctuation
Blood pressure systolic increased
Infection
Limb injury

male:

Abdominal pain
Nausea (feeling of having an urge to vomit)
Hyperlipidaemia (presence of excess lipids in the blood)
Lymphoedema (localized fluid retention and tissue swelling)
Malaise (a feeling of general discomfort or uneasiness)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Stasis dermatitis (skin inflammation caused by blood pooling in the veins in your legs)
Agitation (state of anxiety or nervous excitement)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Cellulitis (infection under the skin)

What are the common drug interactions of Insulin and Demerol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Acute respiratory distress syndrome
Blood bilirubin increased
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Hypotension (abnormally low blood pressure)
Pneumonia respiratory syncytial viral (respiratory syncytial virus (rsv) is a very common virus that leads to mild, cold-like symptoms in adults and older healthy children)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

20-29:

Dysarthria (speech disorder)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Visual field defect
Nervous system disorder (a general class of medical conditions affecting the nervous system)

30-39:

Cardiogenic shock (inadequate circulation of blood)
Injury
Psychiatric symptom
Renal failure (kidney dysfunction)

40-49:

Abdominal pain
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Agitation (state of anxiety or nervous excitement)
Anxiety
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Cellulitis (infection under the skin)
Cholecystitis (infection of gallbladder)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Confusional state

50-59:

Pain in extremity
Blood pressure decreased
Blood pressure increased
Oxygen saturation decreased
Pneumonia
Blood pressure fluctuation
Blood pressure systolic increased
Infection
Limb injury
Lung infection

60+:

Abdominal discomfort
Fatigue (feeling of tiredness)
Pneumonia
Abdominal distension
Anxiety
Feeling hot
Actinic keratosis (skin disease due to sun exposure)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arrhythmia (irregular heartbeat)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 20.41%
Chills (felling of cold): 8 people, 16.33%
Constipation: 7 people, 14.29%
Agitation (state of anxiety or nervous excitement): 6 people, 12.24%
Psoriasis (immune-mediated disease that affects the skin): 6 people, 12.24%
Anaemia (lack of blood): 6 people, 12.24%
Wound: 4 people, 8.16%
Dry Skin: 4 people, 8.16%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 8.16%
Angiopathy (generic term for a disease of the blood vessels): 4 people, 8.16%

* Approximation only. Some reports may have incomplete information.

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