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Intelence and Letairis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Intelence (etravirine) and Letairis (ambrisentan). Common drug interactions include nephrolithiasis among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Intelence and Letairis. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Intelence?

Intelence has active ingredients of etravirine. It is often used in hiv infection. eHealthMe is studying from 3,797 Intelence users. Check the latest studies of Intelence.

What is Letairis?

Letairis has active ingredients of ambrisentan. It is often used in pulmonary hypertension. eHealthMe is studying from 94,041 Letairis users. Check the latest studies of Letairis.

On Jul, 16, 2026

13 people who take Intelence and Letairis together, and have interactions are studied.

Intelence and Letairis drug interactions.

What are the common drug interactions of Intelence and Letairis, by gender? *:

female:

  1. Nephrolithiasis (calculi in the kidneys)
  2. Renal impairment (severely reduced kidney function)
  3. Fluid retention (an abnormal accumulation of fluid in the blood)
  4. Oedema peripheral (superficial swelling)

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Vomiting
  3. Chronic kidney disease
  4. Dyspnoea (difficult or laboured respiration)
  5. Renal failure (kidney dysfunction)
  6. Renal impairment (severely reduced kidney function)
  7. Diarrhoea
  8. Lethargy (tiredness)
  9. Oedema (fluid collection in tissue)
  10. Gastrointestinal disorder (functional problems of gastrointestinal tract)

What are the common drug interactions of Intelence and Letairis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Oedema (fluid collection in tissue)
  2. Nausea (feeling of having an urge to vomit)
  3. Vomiting
  4. Diarrhoea
  5. Lethargy (tiredness)

50-59:

  1. Renal impairment (severely reduced kidney function)
  2. Nephrolithiasis (calculi in the kidneys)
  3. Chronic kidney disease
  4. Renal failure (kidney dysfunction)

60+:

  1. Bradycardia (abnormally slow heart action)
  2. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 8 people, 61.54%
  2. Hiv Infection: 3 people, 23.08%
  3. Indigestion: 1 person, 7.69%
  4. Dyspnea (difficult or laboured breathing): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Intelence and Letairis?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Intelence and Letairis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Intelence:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Letairis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Intelence and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Letairis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on etravirine and ambrisentan (the active ingredients of Intelence and Letairis, respectively), and Intelence and Letairis (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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