Intron a and Sandostatin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Intron a (interferon alfa-2b) and Sandostatin (octreotide acetate). Common drug interactions include blood chromogranin a increased among females and lymphadenopathy among males.
The phase IV clinical study analyzes what interactions people have when they take Intron a and Sandostatin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Intron a?
Intron a has active ingredients of interferon alfa-2b. eHealthMe is studying from 9,320 Intron a users. Check the latest studies of Intron a.
What is Sandostatin?
Sandostatin has active ingredients of octreotide acetate. It is often used in acromegaly. eHealthMe is studying from 46,793 Sandostatin users. Check the latest studies of Sandostatin.
32 people who take Intron a and Sandostatin together, and have interactions are studied.

What are the common drug interactions of Intron A and Sandostatin, by gender? *:
female:
- Blood chromogranin a increased
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Malignant neoplasm progression (cancer tumour came back)
- Metastases to lymph nodes (cancer spreads to lymph node)
- Neoplasm malignant (cancer tumour)
- Disease progression
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hepatic pain (pain in liver)
- Lymphadenopathy (disease or enlargement of lymph nodes)
male:
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Decreased appetite
- Osteonecrosis of jaw (death of bone of jaw)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Weight decreased
- Abdominal discomfort
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Aortic arteriosclerosis (hardening of the aortic arteries)
What are the common drug interactions of Intron A and Sandostatin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Decreased appetite
- Depression
- Drug intolerance (drug sensitivity)
- Fatigue (feeling of tiredness)
- Hypertension (high blood pressure)
- Hypotension (abnormally low blood pressure)
- Neuropathy peripheral (surface nerve damage)
- Osteonecrosis (death of bone)
- Peripheral swelling
- Pleural effusion (water on the lungs)
30-39:
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Disease progression
- Metastases to liver (cancer spreads to liver)
- Malignant neoplasm progression (cancer tumour came back)
- Hepatic mass
40-49:
n/a
50-59:
- Blood triglycerides increased
- Death
- Dementia due to pick's disease (madness due to pick's disease)
- Depressed mood
- Disease progression
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Weight decreased
- Hepatic pain (pain in liver)
- Abdominal pain
60+:
- Abdominal pain
- Arthralgia (joint pain)
- Back pain
- Diarrhoea
- Loss of consciousness
- Pain
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Neoplasm malignant (cancer tumour)
- Abdominal discomfort
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
What are the existing conditions these people have? *
- Metastases To Lymph Nodes (cancer spreads to lymph node): 4 people, 12.50%
- Neuroendocrine Tumor: 3 people, 9.38%
- Neuroendocrine Carcinoma (cancer tumour that arise from cells of the endocrine (hormonal) and nervous systems): 3 people, 9.38%
- Liver Disorder (liver diseases): 3 people, 9.38%
- Osteolysis (dissolution of bone): 2 people, 6.25%
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 2 people, 6.25%
- Angiopathy (generic term for a disease of the blood vessels): 2 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Intron a and Sandostatin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Intron a (9,320 reports)
- Sandostatin (46,793 reports)
Browse all drug interactions of Intron a and Sandostatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Intron a:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sandostatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Intron a and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sandostatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Saif MW, "Rheumatoid arthritis associated with the use of Sandostatin? LAR? depot in a patient with pancreatic neuroendocrine tumor", An association or a coincidence? The first case report, 2017 Jan .
- Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .
- Saif MW, "Rheumatoid arthritis associated with the use of Sandostatin? LAR? depot in a patient with pancreatic neuroendocrine tumor", An association or a coincidence? The first case report, 2017 Jan .
- Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on interferon alfa-2b and octreotide acetate (the active ingredients of Intron a and Sandostatin, respectively), and Intron a and Sandostatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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