Invanz and Hydrochlorothiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Invanz (ertapenem sodium) and Hydrochlorothiazide (hydrochlorothiazide). Common drug interactions include infusion related reaction among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Invanz and Hydrochlorothiazide. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Invanz?

Invanz has active ingredients of ertapenem sodium. It is often used in urinary tract infection. eHealthMe is studying from 3,961 Invanz users. Check the latest studies of Invanz.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,194 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.



On Aug, 06, 2026

83 people who take Invanz and Hydrochlorothiazide together, and have interactions are studied.

Invanz and Hydrochlorothiazide drug interactions.

What are the common drug interactions of Invanz and Hydrochlorothiazide, by gender? *:

female:

  1. Infusion related reaction
  2. Weight decreased
  3. Abdominal pain
  4. Anaemia (lack of blood)
  5. Colitis (inflammation of colon)
  6. Colitis ulcerative (inflammation of colon with ulcer)
  7. Constipation
  8. Erythema (redness of the skin)
  9. Female genital tract fistula (passage in genital tract of female)
  10. Frequent bowel movements

male:

  1. Dehydration (dryness resulting from the removal of water)
  2. Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
  3. Abscess (pus)
  4. Abscess limb (limb infection)
  5. Agitation (state of anxiety or nervous excitement)
  6. Blood sodium decreased
  7. Cellulitis (infection under the skin)
  8. Coagulation time prolonged
  9. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  10. Confusional state

What are the common drug interactions of Invanz and Hydrochlorothiazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anal abscess
  2. Abscess (pus)
  3. Abscess limb (limb infection)
  4. Cellulitis (infection under the skin)
  5. Gangrene (body tissue dies)
  6. Perirectal abscess
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Soft tissue necrosis (death of soft tissue)
  9. Subcutaneous abscess
  10. Depression

40-49:

  1. Dizziness
  2. Drug hypersensitivity
  3. Dysarthria (speech disorder)
  4. Dyspnoea (difficult or laboured respiration)
  5. Flushing (the warm, red condition of human skin)
  6. Lethargy (tiredness)
  7. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Sensation of heaviness

50-59:

  1. Depression
  2. Diarrhoea
  3. Drug ineffective
  4. Dysgeusia (disorder of the sense of taste)
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Hypercalcaemia (elevated calcium (ca+) level in the blood)
  8. Hyperhidrosis (abnormally increased sweating)
  9. Insomnia (sleeplessness)
  10. International normalised ratio increased

60+:

  1. Dyspepsia (indigestion)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
  4. Weight decreased
  5. Abdominal pain
  6. Anaemia (lack of blood)
  7. Colitis (inflammation of colon)
  8. Colitis ulcerative (inflammation of colon with ulcer)
  9. Constipation
  10. Erythema (redness of the skin)

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 33 people, 39.76%
  2. Allergies: 25 people, 30.12%
  3. Pain: 6 people, 7.23%
  4. Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Invanz and Hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Invanz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Invanz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrochlorothiazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ertapenem sodium and hydrochlorothiazide (the active ingredients of Invanz and Hydrochlorothiazide, respectively), and Invanz and Hydrochlorothiazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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