Invega sustenna and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Invega sustenna (paliperidone palmitate) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include dysphagia among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Invega sustenna and Adderall. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Invega sustenna?

Invega sustenna has active ingredients of paliperidone palmitate. It is often used in schizophrenia. eHealthMe is studying from 23,232 Invega sustenna users. Check the latest studies of Invega sustenna.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

On Jul, 10, 2026

74 people who take Invega sustenna and Adderall together, and have interactions are studied.

Invega sustenna and Adderall drug interactions.

What are the common drug interactions of Invega Sustenna and Adderall, by gender? *:

female:

Dysphagia (a condition in which swallowing is difficult or painful)
Emotional distress
Emotional poverty
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Hospitalisation
Inappropriate affect
Multiple allergies (allergy to multiple agents)
Muscle spasms (muscle contraction)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Otorrhoea (discharge from the ear)

male:

Drug ineffective
Injection site pain
Road traffic accident
Antipsychotic drug level increased
Ejaculation failure
Libido increased (increased sexual urge to have sex)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Sensory disturbance (sense disturbance)
Anger
Hallucination (an experience involving the perception of something not present)

What are the common drug interactions of Invega Sustenna and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Euphoric mood (excessively happy but may become angry or irritable)
Galactorrhoea (secretion of breast milk in men)
Alcohol abuse
Drug dependence
Fear
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Therapeutic response decreased (less preventive response)
Tobacco user
Trismus (reduced opening of the jaws)

20-29:

Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Physical assault
Weight increased
Boredom
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Emotional poverty
Hallucination, auditory (perceiving sounds without auditory stimulus)
Increased appetite

30-39:

Injection site pain
Disturbance in attention
Exercise tolerance decreased
Post-traumatic stress disorder
Weight increased
Multiple fractures
Road traffic accident
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Anxiety
Drug effect decreased

40-49:

Antipsychotic drug level increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug ineffective
Ejaculation failure
Gynaecomastia (enlargement of the gland tissue of the male breast)
Headache (pain in head)
Libido increased (increased sexual urge to have sex)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Sensory disturbance (sense disturbance)
Weight increased

50-59:

Otitis externa (external ear infection)
Eye swelling
Nasopharyngitis (inflammation of the nasopharynx)
Respiratory disorder (respiratory disease)
Somnolence (a state of near-sleep, a strong desire for sleep)
Drug ineffective
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Weight increased
Deafness unilateral

60+:

Application site erythema (redness of the skin at application site)
Application site nodule
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight increased

What are the existing conditions these people have? *

Schizoaffective Disorder (a mental disorder characterized by disordered thought): 11 people, 14.86%
Bipolar Disorder (mood disorder): 10 people, 13.51%
Stress And Anxiety: 9 people, 12.16%
Sleep Disorder: 7 people, 9.46%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 8.11%
Schizoaffective Disorder Bipolar Type (mental illness featuring schizophrenia and a mood disorder with mania): 5 people, 6.76%
Depression: 4 people, 5.41%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 4 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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