Invega and Lasix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Invega (paliperidone) and Lasix (furosemide). Common drug interactions include heart rate decreased among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Invega and Lasix. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Invega?

Invega has active ingredients of paliperidone. It is often used in bipolar disorder. eHealthMe is studying from 32,353 Invega users. Check the latest studies of Invega.

What is Lasix?

Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 210,439 Lasix users. Check the latest studies of Lasix.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

54 people who take Invega and Lasix together, and have interactions are studied.

What are the common drug interactions of Invega and Lasix, by gender? *:

female:

Heart rate decreased
Heart rate increased
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypotension (abnormally low blood pressure)
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Infection
Loss of consciousness
Malignant neoplasm progression (cancer tumour came back)
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Mood swings (an extreme or rapid change in mood)

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Dizziness
Cardiac arrest
Lethargy (tiredness)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Abnormal behaviour
Acute myocardial infarction (acute heart attack)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anger

What are the common drug interactions of Invega and Lasix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Ascites (accumulation of fluid in the abdominal cavity)
Biliary dilatation
Cytomegalovirus test positive
Hypervolaemia (abnormally increased volume of blood)
Mycoplasma infection (bacterial infection)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Suicidal ideation
Epstein-barr virus infection

20-29:

n/a

30-39:

Anticonvulsant drug level below therapeutic
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diarrhoea
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Pain
Pulmonary congestion (congestion in the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Cardiac arrest

40-49:

Dyspnoea (difficult or laboured respiration)
Pickwickian syndrome (extreme obesity accompanied by sleepiness, hypoventilation, and polycythemia)
Weight increased
Hyperglycaemia (high blood sugar)
Immune reconstitution syndrome (immune recovery syndrome)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Anger
Apathy
Asthenia (weakness)

50-59:

Renal failure (kidney dysfunction)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Abnormal behaviour
Anxiety
Blood creatinine increased
Blood glucose decreased
Cardiac murmur (an heart sound in valve abnormality)
Chest pain
Chronic kidney disease

60+:

Dizziness
Anxiety
Dry eye (lack of adequate tears)
Infected skin ulcer
Lacrimation decreased
Pneumonia
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Sleep disorder
Weight decreased
Death

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 10 people, 18.52%
Pain: 7 people, 12.96%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 12.96%
High Blood Pressure: 6 people, 11.11%
Diabetes: 6 people, 11.11%
Depression: 6 people, 11.11%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 9.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.26%
Stress And Anxiety: 4 people, 7.41%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 4 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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