Invokana and Korlym drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Invokana (canagliflozin) and Korlym (mifepristone). Common drug interactions include localised infection among females and nausea among males.
The phase IV clinical study analyzes what interactions people have when they take Invokana and Korlym. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.
What is Invokana?
Invokana has active ingredients of canagliflozin. It is often used in diabetes. eHealthMe is studying from 29,937 Invokana users. Check the latest studies of Invokana.
What is Korlym?
Korlym has active ingredients of mifepristone. eHealthMe is studying from 3,078 Korlym users. Check the latest studies of Korlym.
88 people who take Invokana and Korlym together, and have interactions are studied.

What are the common drug interactions of Invokana and Korlym, by gender? *:
female:
- Localised infection (infection at the single location)
- Sinusitis (inflammation of sinus)
- Blood creatinine increased
- Decreased appetite
- Dry mouth
- Joint swelling
- Muscular weakness (muscle weakness)
- Rash erythematous (redness of the skin)
- Rash pruritic (redness with itching)
- Haemoglobin decreased
male:
- Nausea (feeling of having an urge to vomit)
- Blood pressure increased
- Heart rate decreased
- Hypotension (abnormally low blood pressure)
- Incisional hernia (hernia caused by an incompletely-healed surgical wound)
- Oedema (fluid collection in tissue)
- Renal impairment (severely reduced kidney function)
- Blood potassium decreased
- Peripheral swelling
- Blood glucose decreased
What are the common drug interactions of Invokana and Korlym, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Arthralgia (joint pain)
- Blood testosterone increased
- Cold sweat
- Disease complication
- Fatigue (feeling of tiredness)
- Gastric ulcer (stomach ulcer)
- Headache (pain in head)
- Immune system disorder
- Myalgia (muscle pain)
- Nausea (feeling of having an urge to vomit)
40-49:
- Blood glucose increased
- Fatigue (feeling of tiredness)
- Muscular weakness (muscle weakness)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Weight increased
50-59:
- Blood pressure increased
- Cardiac arrest
- Constipation
- Decreased appetite
- Dry mouth
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Peripheral swelling
- Pleural effusion (water on the lungs)
- Pulmonary congestion (congestion in the lungs)
60+:
- Nausea (feeling of having an urge to vomit)
- Fatigue (feeling of tiredness)
- Blood glucose decreased
- Adrenal mass
- Heart rate increased
- Hot flush (sudden feelings of heat)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Insomnia (sleeplessness)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Weight decreased
What are the existing conditions these people have? *
- Cushing's Syndrome (obesity, a rounded face, increased fat): 84 people, 95.45%
* Approximation only. Some reports may have incomplete information.
Do you take Invokana and Korlym?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Invokana and Korlym:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Invokana:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Korlym:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Invokana and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Korlym and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on canagliflozin and mifepristone (the active ingredients of Invokana and Korlym, respectively), and Invokana and Korlym (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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