Isentress and Methyldopa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isentress (raltegravir potassium) and Methyldopa (methyldopa). Common drug interactions include abortion spontaneous among females.

The phase IV clinical study analyzes what interactions people have when they take Isentress and Methyldopa. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Isentress?

Isentress has active ingredients of raltegravir potassium. It is often used in hiv infection. eHealthMe is studying from 16,529 Isentress users. Check the latest studies of Isentress.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.



On Jul, 12, 2026

11 people who take Isentress and Methyldopa together, and have interactions are studied.

Isentress and Methyldopa drug interactions.

What are the common drug interactions of Isentress and Methyldopa, by gender? *:

female:

  1. Abortion spontaneous (naturally occurring miscarriage)
  2. Anaemia (lack of blood)
  3. Respiratory failure (inadequate gas exchange by the respiratory system)
  4. Uterine haematoma (gathering of blood between the membranes of the placenta and the uterus)
  5. Vaginal haemorrhage (vaginal bleeding)
  6. Cerebral infarction (less blood supply to brain resulting tissue damage)
  7. Cerebral ventricle dilatation (enlargement of ventricle of brain)
  8. Drug exposure during pregnancy
  9. Necrosis (the death of body tissue)
  10. Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)

male:

n/a

What are the common drug interactions of Isentress and Methyldopa, by age (0-1 to 60+)? *:

0-1:

  1. Anaemia (lack of blood)
  2. Cardiac failure
  3. Cerebral infarction (less blood supply to brain resulting tissue damage)
  4. Death
  5. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  6. Hydrocephalus (water on the brain)
  7. Hypotension (abnormally low blood pressure)
  8. Hypotonia (low muscle tone)
  9. Intraventricular haemorrhage (intraventricular bleeding)
  10. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abortion spontaneous (naturally occurring miscarriage)
  2. Uterine haematoma (gathering of blood between the membranes of the placenta and the uterus)
  3. Vaginal haemorrhage (vaginal bleeding)
  4. Drug exposure during pregnancy
  5. Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
  6. Drug ineffective
  7. Hepatotoxicity (chemical-driven liver damage)
  8. Premature labour
  9. Stillbirth (a birth of dead foetus)
  10. Vomiting in pregnancy

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 3 people, 27.27%
  2. Depression: 1 person, 9.09%
  3. Constipation: 1 person, 9.09%
  4. Blood Pressure Abnormal: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Isentress and Methyldopa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isentress and Methyldopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isentress:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Methyldopa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isentress and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methyldopa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on raltegravir potassium and methyldopa (the active ingredients of Isentress and Methyldopa, respectively), and Isentress and Methyldopa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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