Isoniazid and Hydrocortisone sodium succinate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoniazid (isoniazid) and Hydrocortisone sodium succinate (hydrocortisone sodium succinate). Common drug interactions include parent-child problem among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Isoniazid and Hydrocortisone sodium succinate. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Hydrocortisone sodium succinate?

Hydrocortisone sodium succinate has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 3,777 Hydrocortisone sodium succinate users. Check the latest studies of Hydrocortisone sodium succinate.



On Jul, 12, 2026

20 people who take Isoniazid and Hydrocortisone sodium succinate together, and have interactions are studied.

Isoniazid and Hydrocortisone sodium succinate drug interactions.

What are the common drug interactions of Isoniazid and Hydrocortisone Sodium Succinate, by gender? *:

female:

  1. Parent-child problem
  2. Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)
  3. Renal failure acute (rapid kidney dysfunction)
  4. Sedation
  5. Serum ferritin increased
  6. Stem cell transplant
  7. Suicidal ideation
  8. Transplant rejection (a transplant material is not worked)
  9. Cytomegalovirus infection
  10. Pericardial effusion (fluid around the heart)

male:

  1. Cellulitis (infection under the skin)
  2. Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
  3. Blood creatinine increased
  4. Blood pressure decreased
  5. Blood urea increased
  6. C-reactive protein increased
  7. Hypercholesterolaemia (high levels of cholesterol in the blood)
  8. Hypercoagulation (increased tendency for clotting of the blood)
  9. Hyperglycaemia (high blood sugar)
  10. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)

What are the common drug interactions of Isoniazid and Hydrocortisone Sodium Succinate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Infection
  2. Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses)
  3. Renal failure acute (rapid kidney dysfunction)
  4. Transplant rejection (a transplant material is not worked)

20-29:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Headache (pain in head)
  3. Interstitial lung disease
  4. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  5. Oedema (fluid collection in tissue)
  6. Platelet count decreased
  7. Pleural effusion (water on the lungs)
  8. Pulmonary haemorrhage (acute bleeding from the lung)
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. White blood cell count decreased

30-39:

  1. Cellulitis (infection under the skin)
  2. Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Fungal infection
  5. Renal failure (kidney dysfunction)
  6. Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)

40-49:

  1. Cytomegalovirus infection
  2. Influenza
  3. Pneumomediastinum (air is present in the mediastinum)
  4. Pneumonia
  5. Acute respiratory failure
  6. Respiratory failure (inadequate gas exchange by the respiratory system)

50-59:

n/a

60+:

  1. Hyperglycaemia (high blood sugar)
  2. Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant)
  3. Cytomegalovirus infection
  4. Cytomegalovirus test positive
  5. Electrolyte imbalance
  6. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  7. Fluid retention (an abnormal accumulation of fluid in the blood)
  8. Fungal infection
  9. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  10. Hepatic mass

What are the existing conditions these people have? *

  1. High Blood Pressure: 8 people, 40.00%
  2. Gastric Ulcer (stomach ulcer): 8 people, 40.00%
  3. Constipation: 6 people, 30.00%
  4. Hypotension (abnormally low blood pressure): 6 people, 30.00%
  5. Insomnia (sleeplessness): 6 people, 30.00%
  6. Cytomegalovirus Infection: 5 people, 25.00%
  7. Oedema (fluid collection in tissue): 4 people, 20.00%
  8. Fever: 4 people, 20.00%
  9. Dyspnea (difficult or laboured breathing): 4 people, 20.00%
  10. Diarrhea: 4 people, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Isoniazid and Hydrocortisone sodium succinate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isoniazid and Hydrocortisone sodium succinate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isoniazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydrocortisone sodium succinate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isoniazid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrocortisone sodium succinate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on isoniazid and hydrocortisone sodium succinate (the active ingredients of Isoniazid and Hydrocortisone sodium succinate, respectively), and Isoniazid and Hydrocortisone sodium succinate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: