Isoniazid and Penicillin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoniazid (isoniazid) and Penicillin (penicillin g potassium). Common drug interactions include alcohol poisoning among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Isoniazid and Penicillin. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Penicillin?

Penicillin has active ingredients of penicillin g potassium. It is often used in strep throat. eHealthMe is studying from 8,567 Penicillin users. Check the latest studies of Penicillin.

On Jul, 16, 2026

72 people who take Isoniazid and Penicillin together, and have interactions are studied.

Isoniazid and Penicillin drug interactions.

What are the common drug interactions of Isoniazid and Penicillin, by gender? *:

female:

Alcohol poisoning
Atelectasis (partial or complete collapse of the lung)
Bipolar disorder (mood disorder)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cellulitis (infection under the skin)
Suicide attempt
Tooth disorder (tooth disease)
Tooth fracture
Drug eruption (adverse drug reaction of the skin)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
International normalised ratio increased
Blood glucose decreased
Blood immunoglobulin a increased
Blood immunoglobulin g increased
Blood immunoglobulin m increased
Coma (state of unconsciousness lasting more than six hours)
Confusional state
Corneal reflex decreased (slow blinking)
Dizziness

What are the common drug interactions of Isoniazid and Penicillin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Eosinophil percentage increased
Hallucination, visual (seeing things that aren't there)
Hyperreflexia (overactive or over responsive reflexes)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Lymphocyte percentage increased
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Nausea (feeling of having an urge to vomit)
Overdose
Psychomotor hyperactivity (feelings of extreme restlessness)

10-19:

Ascites (accumulation of fluid in the abdominal cavity)
Glomerulonephritis acute (rapid group of conditions that affect parts of the kidneys called glomeruli)
Haematuria (presence of blood in urine)
Hypertension (high blood pressure)
Oedema peripheral (superficial swelling)
Proteinuria (presence of protein in the urine)
Pulmonary oedema (fluid accumulation in the lungs)
Renal impairment (severely reduced kidney function)
Type 2 lepra reaction

20-29:

n/a

30-39:

Anogenital warts
Blood hiv rna increased
Kidney infection
Renal failure (kidney dysfunction)
Viral load increased
Anxiety
Depression
Humerus fracture (injury to the upper arm bone)
Tooth loss
Upper limb fracture

40-49:

Gastric disorder (disease of stomach)
Abdominal discomfort
Abdominal pain upper
Arthralgia (joint pain)
Cardiac failure congestive
Cough
Diarrhoea
Drug hypersensitivity
Drug ineffective
Drug intolerance (drug sensitivity)

50-59:

Drug ineffective
Arthralgia (joint pain)
Hepatic steatosis (fatty liver disease)
Hypertension (high blood pressure)
Loss of employment
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Rash
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
International normalised ratio increased

60+:

n/a

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 45 people, 62.50%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 24 people, 33.33%
Abdominal Discomfort: 22 people, 30.56%
Hiv Infection: 9 people, 12.50%
Peripheral Vascular Disorder: 4 people, 5.56%
Mycobacterial Infection: 4 people, 5.56%
Abscess Neck (neck abscesses): 4 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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