Isoniazid and Thiotepa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoniazid (isoniazid) and Thiotepa (thiotepa). Common drug interactions include cytomegalovirus infection among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Isoniazid and Thiotepa. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Thiotepa?

Thiotepa has active ingredients of thiotepa. eHealthMe is studying from 8,097 Thiotepa users. Check the latest studies of Thiotepa.

On Jul, 19, 2026

26 people who take Isoniazid and Thiotepa together, and have interactions are studied.

Isoniazid and Thiotepa drug interactions.

What are the common drug interactions of Isoniazid and Thiotepa, by gender? *:

female:

Cytomegalovirus infection
Mucosal inflammation (infection of mucous membrane)
Respiratory failure (inadequate gas exchange by the respiratory system)
Bacterial sepsis
Idiopathic pneumonia syndrome (pneumonia-like symptoms)
Liver disorder (liver diseases)
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Venoocclusive disease (small veins in the liver are obstructed)
Ascites (accumulation of fluid in the abdominal cavity)

male:

Drug ineffective
Septic shock (shock due to blood infection)
Adenovirus infection
Back pain
Bacterial sepsis
Cytomegalovirus infection
Disseminated tuberculosis
Drug level below therapeutic
Idiopathic pneumonia syndrome (pneumonia-like symptoms)
Liver disorder (liver diseases)

What are the common drug interactions of Isoniazid and Thiotepa, by age (0-1 to 60+)? *:

0-1:

Drug ineffective
Septic shock (shock due to blood infection)

2-9:

Respiratory failure (inadequate gas exchange by the respiratory system)
Bacterial sepsis
Cytomegalovirus infection
Idiopathic pneumonia syndrome (pneumonia-like symptoms)
Liver disorder (liver diseases)
Mucosal inflammation (infection of mucous membrane)
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Venoocclusive disease (small veins in the liver are obstructed)
Renal impairment (severely reduced kidney function)

10-19:

Mitral valve disease (disease of mitral valve of heart)
Mucosal inflammation (infection of mucous membrane)
Nausea (feeling of having an urge to vomit)
Norovirus test positive
Pain
Pancreatitis (inflammation of pancreas)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Rash erythematous (redness of the skin)
Respiratory failure (inadequate gas exchange by the respiratory system)
Rhinovirus infection

20-29:

n/a

30-39:

Ascites (accumulation of fluid in the abdominal cavity)
Pericarditis (inflammation of the pericardium)
Pleural effusion (water on the lungs)
Bacterial sepsis
Cytomegalovirus infection
Idiopathic pneumonia syndrome (pneumonia-like symptoms)
Liver disorder (liver diseases)
Maternal exposure during pregnancy (use of substance during pregnancy)
Mucosal inflammation (infection of mucous membrane)
Premature labour

40-49:

Dyspnoea (difficult or laboured respiration)
Paradoxical drug reaction
Drug level decreased
Adenovirus infection
Back pain
Bacterial sepsis
Cytomegalovirus infection
Disseminated tuberculosis
Drug ineffective
Drug level below therapeutic

50-59:

n/a

60+:

Bacterial sepsis
Cytomegalovirus infection
Venoocclusive disease (small veins in the liver are obstructed)
Idiopathic pneumonia syndrome (pneumonia-like symptoms)
Liver disorder (liver diseases)
Mucosal inflammation (infection of mucous membrane)
Pain
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Bone Marrow Conditioning Regimen: 9 people, 34.62%
Pneumonia Cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses): 4 people, 15.38%
Human Herpesvirus 6 Infection: 4 people, 15.38%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 4 people, 15.38%
Cytomegalovirus Infection: 4 people, 15.38%
Bone Marrow Failure: 4 people, 15.38%
Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 4 people, 15.38%
Pulmonary Tuberculosis (lungs tuberculosis): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

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