Isoptin and Repaglinide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoptin (verapamil hydrochloride) and Repaglinide (repaglinide). Common drug interactions include rash erythematous among females and hypoglycaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Isoptin and Repaglinide. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.

What is Repaglinide?

Repaglinide has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 8,226 Repaglinide users. Check the latest studies of Repaglinide.

On Jul, 16, 2026

21 people who take Isoptin and Repaglinide together, and have interactions are studied.

Isoptin and Repaglinide drug interactions.

What are the common drug interactions of Isoptin and Repaglinide, by gender? *:

female:

Rash erythematous (redness of the skin)
Arthralgia (joint pain)
Cutaneous vasculitis (an inflammatory process affecting the vessel wall that leads to its damage)
Extremity necrosis (death of body tissue of arms and legs)
Henoch-schonlein purpura (inflammation of the blood vessels in the skin and other body organs)
Hypergammaglobulinaemia (elevated levels of gamma globulin)
Idiopathic urticaria (allergic reactions, presence of hives with unknown cause)
Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
Pruritus (severe itching of the skin)
Purpura (purplish discoloration of the skin)

male:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Atrioventricular block (heart block)
Ejection fraction decreased (systolic heart failure)
Fatigue (feeling of tiredness)
Hypotension (abnormally low blood pressure)
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
Mitral valve incompetence (inefficient heart valve)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
N-terminal prohormone brain natriuretic peptide increased
Oedema (fluid collection in tissue)

What are the common drug interactions of Isoptin and Repaglinide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Malaise (a feeling of general discomfort or uneasiness)
Pruritus (severe itching of the skin)
Rash erythematous (redness of the skin)

50-59:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Atrioventricular block (heart block)
Hypotension (abnormally low blood pressure)
Ischaemic hepatitis (decreased blood supply to the liver resulting in injury to liver cells)
Renal failure (kidney dysfunction)
Hyperglycaemia (high blood sugar)
Hypokalaemia (low potassium)

60+:

Idiopathic urticaria (allergic reactions, presence of hives with unknown cause)
Rash erythematous (redness of the skin)
Atrioventricular block (heart block)
Atrioventricular block first degree (heart block first degree)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac failure
Chest discomfort
Dyspnoea (difficult or laboured respiration)
Ejection fraction decreased (systolic heart failure)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Type 2 Diabetes: 9 people, 42.86%
Dyslipidaemia (abnormal amount of lipids): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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