Isosorbide dinitrate and Adderall drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Isosorbide dinitrate (isosorbide dinitrate) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include suicidal ideation among females and amnesia among males.
The phase IV clinical study analyzes what interactions people have when they take Isosorbide dinitrate and Adderall. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Isosorbide dinitrate?
Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.
What is Adderall?
Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.
16 people who take Isosorbide dinitrate and Adderall together, and have interactions are studied.

What are the common drug interactions of Isosorbide Dinitrate and Adderall, by gender? *:
female:
- Suicidal ideation
- Surgery
- Adverse drug reaction
- Atrioventricular block (heart block)
- Bell's palsy (facial paralysis)
- Blood creatinine decreased
- Blood pressure decreased
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Drug abuse
male:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Facial bones fracture (bone fracture of face)
- Fall
- Loss of consciousness
- Swelling
- Tooth fracture
- Arrhythmia (irregular heartbeat)
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Chest pain
What are the common drug interactions of Isosorbide Dinitrate and Adderall, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Adverse drug reaction
- Atrioventricular block (heart block)
- Bell's palsy (facial paralysis)
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Death
- Endocarditis (inflammation in heart muscle)
- Surgery
- Vitamin b1 increased
60+:
- Suicidal ideation
- Blood creatinine decreased
- Pneumonia
- Pulmonary mass
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
- Sinusitis (inflammation of sinus)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Surgery
- Tobacco abuse
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 75.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 37.50%
- Drowsiness: 2 people, 12.50%
- Tardive Dyskinesia (a disorder that involves involuntary movements): 1 person, 6.25%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Isosorbide dinitrate and Adderall?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Isosorbide dinitrate (13,180 reports)
- Adderall (64,224 reports)
Browse all drug interactions of Isosorbide dinitrate and Adderall:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Isosorbide dinitrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Adderall:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Isosorbide dinitrate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Adderall and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on isosorbide dinitrate and amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Isosorbide dinitrate and Adderall, respectively), and Isosorbide dinitrate and Adderall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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