Isosorbide dinitrate and Dopamine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isosorbide dinitrate (isosorbide dinitrate) and Dopamine hydrochloride (dopamine hydrochloride). Common drug interactions include blood lactate dehydrogenase increased among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Isosorbide dinitrate and Dopamine hydrochloride. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.

What is Dopamine hydrochloride?

Dopamine hydrochloride has active ingredients of dopamine hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 1,789 Dopamine hydrochloride users. Check the latest studies of Dopamine hydrochloride.



On Jul, 09, 2026

44 people who take Isosorbide dinitrate and Dopamine hydrochloride together, and have interactions are studied.

Isosorbide dinitrate and Dopamine hydrochloride drug interactions.

What are the common drug interactions of Isosorbide Dinitrate and Dopamine Hydrochloride, by gender? *:

female:

  1. Blood lactate dehydrogenase increased
  2. Circulatory collapse
  3. Conjunctivitis (pink eye)
  4. Gamma-glutamyltransferase increased
  5. Pruritus (severe itching of the skin)
  6. Rash
  7. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  8. Dyskinesia (abnormality or impairment of voluntary movement)
  9. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  10. Oxygen saturation decreased

male:

  1. Pyrexia (fever)
  2. Pneumonia
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Melaena (the passage of black, tarry stools)
  5. Oliguria (not enough urine)
  6. Aspartate aminotransferase increased
  7. Blood lactate dehydrogenase increased
  8. Multi-organ failure (multisystem organ failure)
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Acute myocardial infarction (acute heart attack)

What are the common drug interactions of Isosorbide Dinitrate and Dopamine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Aspartate aminotransferase increased
  3. Beta 2 microglobulin increased
  4. Blood albumin decreased
  5. Blood cholesterol decreased
  6. Blood urea increased
  7. Conjunctivitis (pink eye)
  8. Erythema (redness of the skin)
  9. Multi-organ failure (multisystem organ failure)
  10. Protein total decreased

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal distension
  2. Diarrhoea
  3. Incision site pain
  4. Pyrexia (fever)
  5. Upper respiratory tract infection

50-59:

  1. Diarrhoea
  2. Drug ineffective
  3. Electrocardiogram st segment depression
  4. Faeces discoloured
  5. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  6. Injection site haemorrhage (bleeding from injection site)
  7. Interstitial lung disease
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Melaena (the passage of black, tarry stools)
  10. Platelet aggregation nos increased

60+:

  1. Pyrexia (fever)
  2. Cardiac failure
  3. Acute myocardial infarction (acute heart attack)
  4. Blood urea increased
  5. Dyspnoea (difficult or laboured respiration)
  6. Hyperglycaemia (high blood sugar)
  7. Ileal ulcer
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Circulatory collapse
  10. Conjunctivitis (pink eye)

What are the existing conditions these people have? *

  1. Cardiac Failure: 11 people, 25.00%
  2. High Blood Pressure: 11 people, 25.00%
  3. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 9 people, 20.45%
  4. Sleep Disorder: 7 people, 15.91%
  5. Heart Disease: 7 people, 15.91%
  6. Sedation: 7 people, 15.91%
  7. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 6 people, 13.64%
  8. Hypokalemia (low potassium): 6 people, 13.64%
  9. Blood Potassium Decreased: 5 people, 11.36%
  10. Blood Glucose Increased: 5 people, 11.36%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide dinitrate and Dopamine hydrochloride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isosorbide dinitrate and Dopamine hydrochloride:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isosorbide dinitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dopamine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isosorbide dinitrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dopamine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide dinitrate and dopamine hydrochloride (the active ingredients of Isosorbide dinitrate and Dopamine hydrochloride, respectively), and Isosorbide dinitrate and Dopamine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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