Isosorbide dinitrate and Exidine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Isosorbide dinitrate (isosorbide dinitrate) and Exidine (chlorhexidine gluconate). Common drug interactions include alanine aminotransferase increased among females and pyrexia among males.
The phase IV clinical study analyzes what interactions people have when they take Isosorbide dinitrate and Exidine. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Isosorbide dinitrate?
Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.
What is Exidine?
Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.
44 people who take Isosorbide dinitrate and Exidine together, and have interactions are studied.

What are the common drug interactions of Isosorbide Dinitrate and Exidine, by gender? *:
female:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Blood alkaline phosphatase increased
- Constipation
- Cough
- Decreased appetite
- Diarrhoea
- Epigastric discomfort
- Gingivitis (inflammation of gums)
- Hypokalaemia (low potassium)
male:
- Pyrexia (fever)
- Dyspnoea (difficult or laboured respiration)
- Sputum discoloured
- Anaemia (lack of blood)
- Cardiomegaly (increased size of heart than normal)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Pain
- Apnoea (suspension of external breathing)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
What are the common drug interactions of Isosorbide Dinitrate and Exidine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Cardiac failure congestive
- Chest discomfort
- Cough
- Dizziness
- Dyspnoea at rest (difficult or laboured breathing during rest)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Ill-defined disorder
- Injury
- Oedema peripheral (superficial swelling)
- Surgery
50-59:
- Abscess limb (limb infection)
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Blood alkaline phosphatase increased
- Constipation
- Cough
- Decreased appetite
- Diarrhoea
- Epigastric discomfort
- Gingivitis (inflammation of gums)
60+:
- Pyrexia (fever)
- Dyspnoea (difficult or laboured respiration)
- Anxiety
- Anaemia (lack of blood)
- Apnoea (suspension of external breathing)
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Arthropathy
- Asthenia (weakness)
- Back pain
What are the existing conditions these people have? *
- High Blood Pressure: 14 people, 31.82%
- Multiple Myeloma (cancer of the plasma cells): 13 people, 29.55%
- Cough: 12 people, 27.27%
- High Blood Cholesterol: 11 people, 25.00%
- Insomnia (sleeplessness): 10 people, 22.73%
- Pneumonia: 10 people, 22.73%
- Constipation: 10 people, 22.73%
- Fever: 10 people, 22.73%
- The Flu (the flu is caused by an influenza virus): 9 people, 20.45%
- Hypokalemia (low potassium): 9 people, 20.45%
* Approximation only. Some reports may have incomplete information.
Do you take Isosorbide dinitrate and Exidine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Isosorbide dinitrate (13,180 reports)
- Exidine (17,299 reports)
Browse all drug interactions of Isosorbide dinitrate and Exidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Isosorbide dinitrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Exidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Isosorbide dinitrate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Exidine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on isosorbide dinitrate and chlorhexidine gluconate (the active ingredients of Isosorbide dinitrate and Exidine, respectively), and Isosorbide dinitrate and Exidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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