Isosorbide dinitrate and Integrilin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Isosorbide dinitrate (isosorbide dinitrate) and Integrilin (eptifibatide). Common drug interactions include dyslipidaemia among females and injury among males.
The phase IV clinical study analyzes what interactions people have when they take Isosorbide dinitrate and Integrilin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Isosorbide dinitrate?
Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.
What is Integrilin?
Integrilin has active ingredients of eptifibatide. eHealthMe is studying from 3,037 Integrilin users. Check the latest studies of Integrilin.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
20 people who take Isosorbide dinitrate and Integrilin together, and have interactions are studied.

What are the common drug interactions of Isosorbide Dinitrate and Integrilin, by gender? *:
female:
- Dyslipidaemia (abnormal amount of lipids)
- Dyspnoea (difficult or laboured respiration)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Fatigue (feeling of tiredness)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Hypotension (abnormally low blood pressure)
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Nausea (feeling of having an urge to vomit)
- Palpitations (feelings or sensations that your heart is pounding or racing)
male:
- Injury
- Pain
- Arthralgia (joint pain)
- Asthenia (weakness)
- Balance disorder
- Breath sounds
- Cardiac failure congestive
- Cardiac murmur (an heart sound in valve abnormality)
- Cardiomegaly (increased size of heart than normal)
- Cardiomyopathy (weakening of the heart muscle)
What are the common drug interactions of Isosorbide Dinitrate and Integrilin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anxiety
- Death
- Emotional distress
- Fear
- Injury
- Multi-organ failure (multisystem organ failure)
- Pain
- Renal failure (kidney dysfunction)
- Renal impairment (severely reduced kidney function)
- Renal injury (kidney injury)
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Fear
- Injury
- Pain
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Stress
60+:
- Injury
- Pain
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
- Angioplasty
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arrhythmia (irregular heartbeat)
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Arthralgia (joint pain)
- Arthropathy
- Asthenia (weakness)
What are the existing conditions these people have? *
- Acute Myocardial Infarction (acute heart attack): 7 people, 35.00%
- Haemodynamic Instability (disturbances in the blood movement in our body): 6 people, 30.00%
- Pulmonary Embolism (blockage of the main artery of the lung): 6 people, 30.00%
- Stable Angina (a constant chest pain): 2 people, 10.00%
- Chest Pain: 2 people, 10.00%
- Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 2 people, 10.00%
- Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 2 people, 10.00%
- High Blood Pressure: 2 people, 10.00%
- Pain: 2 people, 10.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Isosorbide dinitrate and Integrilin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Isosorbide dinitrate (13,180 reports)
- Integrilin (3,037 reports)
Browse all drug interactions of Isosorbide dinitrate and Integrilin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Isosorbide dinitrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Integrilin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Isosorbide dinitrate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Integrilin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on isosorbide dinitrate and eptifibatide (the active ingredients of Isosorbide dinitrate and Integrilin, respectively), and Isosorbide dinitrate and Integrilin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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