Isosorbide dinitrate and Ultracet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isosorbide dinitrate (isosorbide dinitrate) and Ultracet (acetaminophen; tramadol hydrochloride). Common drug interactions include myocardial infarction among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Isosorbide dinitrate and Ultracet. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.

What is Ultracet?

Ultracet has active ingredients of acetaminophen; tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 6,351 Ultracet users. Check the latest studies of Ultracet.

On Jul, 21, 2026

30 people who take Isosorbide dinitrate and Ultracet together, and have interactions are studied.

Isosorbide dinitrate and Ultracet drug interactions.

What are the common drug interactions of Isosorbide Dinitrate and Ultracet, by gender? *:

female:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Rash pruritic (redness with itching)
Pneumonia
Abnormal faeces (abnormal stool)
Acute respiratory failure
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic disorder
Arthralgia (joint pain)
Basophil count increased
Blood glucose increased

male:

Pneumonia
Cachexia (loss of weight)
Haemoglobin decreased
Hip fracture
Nausea (feeling of having an urge to vomit)
Occult blood (blood in the faeces that is not visibly apparent)
Productive cough
Pyrexia (fever)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough

What are the common drug interactions of Isosorbide Dinitrate and Ultracet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cardiac failure congestive
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

n/a

60+:

Pneumonia
Cachexia (loss of weight)
Arthralgia (joint pain)
Basophil count increased
Blood glucose increased
Blood magnesium increased
Blood potassium increased
Blood urea increased
Bone callus excessive (excessive bony deposit formed between and around the broken ends of bone fractures)
Contusion (a type of hematoma of tissue in which capillaries)

What are the existing conditions these people have? *

High Blood Pressure: 15 people, 50.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 36.67%
Constipation: 11 people, 36.67%
Cough: 10 people, 33.33%
High Blood Cholesterol: 9 people, 30.00%
Diabetes: 9 people, 30.00%
Type 2 Diabetes: 8 people, 26.67%
Stable Angina (a constant chest pain): 7 people, 23.33%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 7 people, 23.33%
Multiple Myeloma (cancer of the plasma cells): 7 people, 23.33%

* Approximation only. Some reports may have incomplete information.

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