Isosorbide mononitrate and Axid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isosorbide mononitrate (isosorbide mononitrate) and Axid (nizatidine). Common drug interactions include cardiac failure congestive among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Isosorbide mononitrate and Axid. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Axid?

Axid has active ingredients of nizatidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 2,980 Axid users. Check the latest studies of Axid.



On Aug, 01, 2026

13 people who take Isosorbide mononitrate and Axid together, and have interactions are studied.

Isosorbide mononitrate and Axid drug interactions.

What are the common drug interactions of Isosorbide Mononitrate and Axid, by gender? *:

female:

  1. Cardiac failure congestive
  2. Chest pain
  3. Nausea (feeling of having an urge to vomit)
  4. Arrhythmia (irregular heartbeat)
  5. Cardiac flutter (abnormal heart rhythm)
  6. Chorea (abnormal involuntary movement disorder)
  7. Chronic kidney disease
  8. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  9. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  10. Disturbance in attention

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Bone disorder
  4. Cardiac disorder
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Diarrhoea
  9. Drug hypersensitivity
  10. Dry mouth

What are the common drug interactions of Isosorbide Mononitrate and Axid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Androgen deficiency
  2. Bone disorder
  3. Cardiac disorder
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Chest pain
  6. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  7. Depression
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Drug ineffective
  10. Fatigue (feeling of tiredness)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Blood glucose increased
  4. Cardiac flutter (abnormal heart rhythm)
  5. Chest pain
  6. Chorea (abnormal involuntary movement disorder)
  7. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  8. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  9. Depression
  10. Diarrhoea

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 6 people, 46.15%
  2. High Blood Pressure: 6 people, 46.15%
  3. Indigestion: 4 people, 30.77%
  4. Joint Pain: 3 people, 23.08%
  5. Headache (pain in head): 3 people, 23.08%
  6. Diabetes: 3 people, 23.08%
  7. Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 23.08%
  8. Nasopharyngitis (inflammation of the nasopharynx): 2 people, 15.38%
  9. Urine Flow Decreased: 2 people, 15.38%
  10. Blood Calcium Decreased: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide mononitrate and Axid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isosorbide mononitrate and Axid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isosorbide mononitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Axid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isosorbide mononitrate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Axid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide mononitrate and nizatidine (the active ingredients of Isosorbide mononitrate and Axid, respectively), and Isosorbide mononitrate and Axid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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