Isosorbide mononitrate and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isosorbide mononitrate (isosorbide mononitrate) and Keppra (levetiracetam). Common drug interactions include abdominal discomfort among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Isosorbide mononitrate and Keppra. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

On Jul, 14, 2026

95 people who take Isosorbide mononitrate and Keppra together, and have interactions are studied.

Isosorbide mononitrate and Keppra drug interactions.

What are the common drug interactions of Isosorbide Mononitrate and Keppra, by gender? *:

female:

Abdominal discomfort
Abscess limb (limb infection)
Anxiety
Arthralgia (joint pain)
Cardiac failure
Chronic kidney disease
Decreased appetite
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)

male:

Vomiting
Nausea (feeling of having an urge to vomit)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
General physical health deterioration (weak health status)
Loss of consciousness
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Weight decreased
Chest pain
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

What are the common drug interactions of Isosorbide Mononitrate and Keppra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Arthralgia (joint pain)
Blood creatine phosphokinase increased
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Vomiting
Brain stem glioma (cancerous glioma tumour in the brainstem)
Decreased appetite
Diarrhoea

20-29:

Fall
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Visual impairment

30-39:

n/a

40-49:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Partial seizures (seizures which affect only a part of the brain at onset)
Blood pressure decreased
Cellulitis (infection under the skin)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Device related infection
Dyspnoea (difficult or laboured respiration)
Fall
Herpes zoster

50-59:

Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Flatulence (flatus expelled through the anus)
Haemoglobin decreased
Headache (pain in head)
Hepatic enzyme increased
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Ill-defined disorder
Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue)
Memory impairment

60+:

Nausea (feeling of having an urge to vomit)
Vomiting
Pain
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dementia (madness)
General physical health deterioration (weak health status)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 13 people, 13.68%
High Blood Pressure: 13 people, 13.68%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 11.58%
High Blood Cholesterol: 10 people, 10.53%
Multiple Myeloma (cancer of the plasma cells): 8 people, 8.42%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 7.37%
Chest Pain: 7 people, 7.37%
Stress And Anxiety: 6 people, 6.32%
Prostatomegaly (enlargement of the prostate): 6 people, 6.32%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 6 people, 6.32%

* Approximation only. Some reports may have incomplete information.

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