Aventyl and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Aventyl (nortriptyline hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Aimovig, and have Migraine.

The phase IV clinical study analyzes which people have Headache when taking Aventyl. It is created by eHealthMe based on reports of 462 people who have side effects when taking Aventyl from the FDA, and is updated regularly.

What is Aventyl?

Aventyl has active ingredients of nortriptyline hydrochloride. eHealthMe is studying from 515 Aventyl users. Check the latest studies of Aventyl.

What is Headache?

Headache (pain in head) is found to be associated with 3,747 drugs and 5,770 conditions by eHealthMe. Check the latest studies of Headache.

On Jul, 14, 2026

462 people reported to have side effects when taking Aventyl.
Among them, 54 people (11.69%) have Headache.

Among these 54 people:

How long have people been on Aventyl when they have Headache? *

What is the gender of people who have Headache when taking Aventyl? *

female: 84.31 %
male: 15.69 %

What is the age of people who have Headache when taking Aventyl? *

What are other drugs people take besides Aventyl? *

What are other side effects people have besides Headache? *

Nausea (feeling of having an urge to vomit): 22 people, 40.74%
Dizziness: 20 people, 37.04%
Drug Ineffective: 17 people, 31.48%
Fatigue (feeling of tiredness): 16 people, 29.63%
Migraine (headache): 15 people, 27.78%
Joint Pain: 15 people, 27.78%
High Blood Pressure: 14 people, 25.93%
Back Pain: 13 people, 24.07%
Pain In Extremity: 13 people, 24.07%
Abdominal Pain: 12 people, 22.22%

What are the existing conditions these people have? *

Migraine (headache): 20 people, 37.04%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 12.96%
Pain: 6 people, 11.11%
Medullary Thyroid Cancer (type of thyroid cancer that develops in the parafollicular cells of the thyroid gland): 5 people, 9.26%
Stress And Anxiety: 5 people, 9.26%
Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 5 people, 9.26%
Post-Traumatic Stress Disorder: 5 people, 9.26%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 9.26%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 7.41%
Osteoporosis (bones weak and more likely to break): 4 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Aventyl and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aventyl:

Aventyl (515 reports)

Headache treatments and more:

Headache (756,642 reports)

Browse all side effects of Aventyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Headache (3,747 drugs)

Browse all the conditions that are associated with Headache:

Headache (5,770 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nortriptyline hydrochloride (the active ingredients of Aventyl) and Aventyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.