Ispaghula and Levothyroxine sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ispaghula (blond psyllium) and Levothyroxine sodium (levothyroxine sodium). Common drug interactions include balance disorder among females and depressed mood among males.

The phase IV clinical study analyzes what interactions people have when they take Ispaghula and Levothyroxine sodium. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Ispaghula?

Ispaghula has active ingredients of blond psyllium. eHealthMe is studying from 737 Ispaghula users. Check the latest studies of Ispaghula.

What is Levothyroxine sodium?

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 129,812 Levothyroxine sodium users. Check the latest studies of Levothyroxine sodium.

On Jul, 20, 2026

40 people who take Ispaghula and Levothyroxine sodium together, and have interactions are studied.

Ispaghula and Levothyroxine sodium drug interactions.

What are the common drug interactions of Ispaghula and Levothyroxine Sodium, by gender? *:

female:

Balance disorder
Blood calcium decreased
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Constipation
Creatinine renal clearance decreased
Depressed level of consciousness
Fall
Hypotension (abnormally low blood pressure)
Mobility decreased (ability to move is reduced)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)

male:

Depressed mood
Restlessness (not able to rest)
Gout (uric acid crystals building up in the body)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Restless legs syndrome (a powerful urge to move your legs)
Seborrhoeic dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp)
Abdominal pain
Constipation

What are the common drug interactions of Ispaghula and Levothyroxine Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Depressed mood
Drug ineffective

50-59:

Abdominal pain
Constipation
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Febrile neutropenia (fever with reduced white blood cells)
Gout (uric acid crystals building up in the body)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Oedema peripheral (superficial swelling)
Seborrhoeic dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp)

60+:

Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Balance disorder
Sedation
Pain
Restlessness (not able to rest)
Chest discomfort
Dizziness
Palpitations (feelings or sensations that your heart is pounding or racing)
Drug abuse
Hyponatraemic syndrome (serum sodium concentration below 135 mmol/l)

What are the existing conditions these people have? *

Constipation: 18 people, 45.00%
Stable Angina (a constant chest pain): 17 people, 42.50%
Insomnia (sleeplessness): 17 people, 42.50%
High Blood Pressure: 17 people, 42.50%
Urinary Tract Infection: 16 people, 40.00%
Thyroid Diseases: 16 people, 40.00%
Bladder Disorder: 16 people, 40.00%
Chest Pain: 16 people, 40.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 16 people, 40.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 16 people, 40.00%

* Approximation only. Some reports may have incomplete information.

Do you take Ispaghula and Levothyroxine sodium?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously