Jakafi and Cleocin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Jakafi (ruxolitinib phosphate) and Cleocin (clindamycin phosphate). Common drug interactions include anaemia among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Jakafi and Cleocin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Jakafi?

Jakafi has active ingredients of ruxolitinib phosphate. It is often used in primary myelofibrosis. eHealthMe is studying from 56,530 Jakafi users. Check the latest studies of Jakafi.

What is Cleocin?

Cleocin has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 3,940 Cleocin users. Check the latest studies of Cleocin.



On Aug, 09, 2026

12 people who take Jakafi and Cleocin together, and have interactions are studied.

Jakafi and Cleocin drug interactions.

What are the common drug interactions of Jakafi and Cleocin, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Dizziness
  3. Fatigue (feeling of tiredness)
  4. Haematocrit decreased
  5. Hot flush (sudden feelings of heat)
  6. Iron overload
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Memory impairment
  9. Red blood cell count decreased
  10. White blood cell count decreased

male:

  1. Cough
  2. Disease progression
  3. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  4. Fatigue (feeling of tiredness)
  5. Haemochromatosis (body to absorb more iron than usual from food)
  6. Iron overload
  7. Renal disorder (kidney disease)
  8. Renal failure (kidney dysfunction)
  9. Renal impairment (severely reduced kidney function)
  10. Weight decreased

What are the common drug interactions of Jakafi and Cleocin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Anaemia (lack of blood)
  2. Dizziness
  3. Fatigue (feeling of tiredness)
  4. Haematocrit decreased
  5. Hot flush (sudden feelings of heat)
  6. Iron overload
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Memory impairment
  9. Red blood cell count decreased
  10. White blood cell count decreased

60+:

  1. Cough
  2. Disease progression
  3. Pneumonia
  4. Weight increased
  5. Arthralgia (joint pain)
  6. Joint crepitation
  7. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  8. Fatigue (feeling of tiredness)
  9. Haemochromatosis (body to absorb more iron than usual from food)
  10. Iron overload

What are the existing conditions these people have? *

  1. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 25.00%
  2. Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 2 people, 16.67%
  3. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 8.33%
  4. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 1 person, 8.33%
  5. Nausea And Vomiting: 1 person, 8.33%
  6. Nausea (feeling of having an urge to vomit): 1 person, 8.33%
  7. High Blood Pressure: 1 person, 8.33%
  8. Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Jakafi and Cleocin?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Jakafi and Cleocin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Jakafi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cleocin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Jakafi and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cleocin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ruxolitinib phosphate and clindamycin phosphate (the active ingredients of Jakafi and Cleocin, respectively), and Jakafi and Cleocin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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