Januvia and Emgality drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Emgality (galcanezumab-gnlm). Common drug interactions include diarrhoea among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Januvia and Emgality. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Januvia?
Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.
What is Emgality?
Emgality has active ingredients of galcanezumab-gnlm. eHealthMe is studying from 24,702 Emgality users. Check the latest studies of Emgality.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
26 people who take Januvia and Emgality together, and have interactions are studied.

What are the common drug interactions of Januvia and Emgality, by gender? *:
female:
- Diarrhoea
- Dysphagia (a condition in which swallowing is difficult or painful)
- Injection site bruising
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
- Pain
- Weight decreased
- Corneal abrasion (loss of the surface of cornea)
- Fatigue (feeling of tiredness)
- Skin cancer
male:
- Arthralgia (joint pain)
- Balance disorder
- Fatigue (feeling of tiredness)
- Head injury
- Headache (pain in head)
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Nausea (feeling of having an urge to vomit)
- Occipital neuralgia (a condition characterized by chronic pain in the upper neck)
- Post-traumatic headache
What are the common drug interactions of Januvia and Emgality, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Constipation
- Contusion (a type of hematoma of tissue in which capillaries)
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Fatigue (feeling of tiredness)
- Hospitalisation
- Insomnia (sleeplessness)
- Pneumonia
- Pyrexia (fever)
50-59:
- Drug ineffective
- Fatigue (feeling of tiredness)
- Pain
- Nausea (feeling of having an urge to vomit)
- Alopecia (absence of hair from areas of the body)
- Headache (pain in head)
- Infection
- Arthralgia (joint pain)
- Balance disorder
- Blood glucose increased
60+:
- Diarrhoea
- Corneal abrasion (loss of the surface of cornea)
- Chest pain
- Death
- Hypertension (high blood pressure)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Injection site bruising
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
- Skin cancer
What are the existing conditions these people have? *
- Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 5 people, 19.23%
- Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 2 people, 7.69%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.69%
- Migraine (headache): 2 people, 7.69%
- Immunodeficiency Common Variable: 2 people, 7.69%
- Immunodeficiency: 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Januvia and Emgality?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Januvia and Emgality:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Januvia:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Emgality:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Januvia and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Emgality and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Liao KF, Lin CL, Lai SW, Chen WC, "Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan", European journal of internal medicine, 2016 Jan .
- Belice T, Yuce S, Kizilkaya B, Kurt A, Cure E, "Noncardiac pulmonary edema induced by sitagliptin treatment", Journal of family medicine and primary care, 2014 Jan .
- Misgar, R. A., Bhat, J. A., Wani, A. I., & Bashir, M. I., "Sitagliptin induced splenic infarcts", Clinical Diabetology, 2014 Jan .
- Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
- Liao KF, Lin CL, Lai SW, Chen WC, "Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan", European journal of internal medicine, 2016 Jan .
- Belice T, Yuce S, Kizilkaya B, Kurt A, Cure E, "Noncardiac pulmonary edema induced by sitagliptin treatment", Journal of family medicine and primary care, 2014 Jan .
- Misgar, R. A., Bhat, J. A., Wani, A. I., & Bashir, M. I., "Sitagliptin induced splenic infarcts", Clinical Diabetology, 2014 Jan .
- Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on sitagliptin phosphate and galcanezumab-gnlm (the active ingredients of Januvia and Emgality, respectively), and Januvia and Emgality (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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