Januvia and Glynase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Glynase (glyburide). Common drug interactions include dizziness among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Januvia and Glynase. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Januvia?

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.

What is Glynase?

Glynase has active ingredients of glyburide. eHealthMe is studying from 1,513 Glynase users. Check the latest studies of Glynase.

On Jul, 30, 2026

18 people who take Januvia and Glynase together, and have interactions are studied.

What are the common drug interactions of Januvia and Glynase, by gender? *:

female:

Dizziness
Drug intolerance (drug sensitivity)
Gait disturbance
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Urticaria (rash of round, red welts on the skin that itch intensely)
Decreased appetite
Eye swelling
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Haematemesis (vomiting of blood)

male:

Blood creatinine increased
Constipation
Decreased appetite
Drug ineffective
Epistaxis (bleed from the nose)
Follicular thyroid cancer (cancer of the thyroid)
Oedema peripheral (superficial swelling)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Post procedural hypothyroidism
Rhinorrhoea (watery mucus discharge from the nose)

What are the common drug interactions of Januvia and Glynase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Follicular thyroid cancer (cancer of the thyroid)
Post procedural hypothyroidism

60+:

Decreased appetite
Dizziness
Epistaxis (bleed from the nose)
Eye swelling
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Hallucination (an experience involving the perception of something not present)
Malaise (a feeling of general discomfort or uneasiness)
Migraine (headache)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

Type 2 Diabetes: 12 people, 66.67%
High Blood Pressure: 2 people, 11.11%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 5.56%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 5.56%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.56%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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