Januvia and Plendil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Plendil (felodipine). Common drug interactions include dysphagia among females and haematuria among males.

The phase IV clinical study analyzes what interactions people have when they take Januvia and Plendil. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Januvia?

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.

On Jul, 27, 2026

49 people who take Januvia and Plendil together, and have interactions are studied.

What are the common drug interactions of Januvia and Plendil, by gender? *:

female:

Dysphagia (a condition in which swallowing is difficult or painful)
Pain
Fall
Abdominal pain upper
Cough
Pain in extremity
Abdominal discomfort
Adverse event
Blindness
Blood glucose decreased

male:

Haematuria (presence of blood in urine)
Oedema peripheral (superficial swelling)
Back pain
Bladder cancer
Bladder mass
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Carotid artery disease

What are the common drug interactions of Januvia and Plendil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Arrhythmia (irregular heartbeat)
Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Arthralgia (joint pain)
Arthropathy
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrophy (wasting away of a part of the body)
Back pain
Bladder cancer

30-39:

n/a

40-49:

n/a

50-59:

Renal injury (kidney injury)
Renal failure (kidney dysfunction)
Adrenal neoplasm (abnormal growth of adrenal gland)
Benign neoplasm of adrenal gland (benign (non-cancerous) tumours of the adrenal gland)
Bladder transitional cell carcinoma (types of bladder cancer)
Chest discomfort
Chronic kidney disease
Haematuria (presence of blood in urine)
Ketoacidosis (high concentrations of ketone bodies in blood)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

60+:

Pain
Blood glucose increased
Blood potassium decreased
Blood pressure decreased
Blood sodium decreased
Bone disorder
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphonia (speech disorder attributable to a disorder of phonation)

What are the existing conditions these people have? *

Bone Disorder: 13 people, 26.53%
Multiple Myeloma (cancer of the plasma cells): 10 people, 20.41%
Type 2 Diabetes: 5 people, 10.20%
Prostatic Disorder: 3 people, 6.12%
Indigestion: 3 people, 6.12%
High Blood Cholesterol: 3 people, 6.12%
Heart Rate Irregular: 3 people, 6.12%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.12%
Cardiac Disorder: 3 people, 6.12%
Brain Neoplasm (tumour of brain): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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