Jardiance and Requip drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Jardiance (empagliflozin) and Requip (ropinirole hydrochloride). Common drug interactions include obesity among females and bile duct obstruction among males.

The phase IV clinical study analyzes what interactions people have when they take Jardiance and Requip. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Jardiance?

Jardiance has active ingredients of empagliflozin. It is often used in hyperglycemia. eHealthMe is studying from 44,457 Jardiance users. Check the latest studies of Jardiance.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

On Jul, 09, 2026

42 people who take Jardiance and Requip together, and have interactions are studied.

What are the common drug interactions of Jardiance and Requip, by gender? *:

female:

Obesity (having too much body fat)
Oedema peripheral (superficial swelling)
Optic nerve injury
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain
Pancreatitis (inflammation of pancreas)
Procedural pain
Rash
Rash erythematous (redness of the skin)
Rash pruritic (redness with itching)

male:

Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Blood pressure decreased
Type 2 diabetes mellitus
Chills (felling of cold)
Dyspnoea (difficult or laboured respiration)
Intestinal obstruction
Muscle spasms (muscle contraction)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Hepatic enzyme increased
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)

What are the common drug interactions of Jardiance and Requip, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Fall
Hypoaesthesia (reduced sense of touch or sensation)
Pancreatitis (inflammation of pancreas)
Renal disorder (kidney disease)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Vulval abscess
Adjustment disorder
Anxiety
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Blood iron decreased
Depression
Dysmenorrhoea (painful menstruation)
Fatigue (feeling of tiredness)
Fungal infection

50-59:

Chills (felling of cold)
Fungal infection
Vomiting
Cough
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Disturbance in attention
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Acute respiratory failure
Asthma

60+:

Muscle spasms (muscle contraction)
Overdose
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Heart rate increased
Hip arthroplasty
Hypersomnia (excessive daytime sleepiness (eds))
Hypoaesthesia (reduced sense of touch or sensation)
Hypoglycaemic seizure (low blood sugar)

What are the existing conditions these people have? *

Type 2 Diabetes: 10 people, 23.81%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 16.67%
Psoriasis (immune-mediated disease that affects the skin): 5 people, 11.90%
Nausea And Vomiting: 5 people, 11.90%
Diabetes: 5 people, 11.90%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 11.90%
Stress And Anxiety: 4 people, 9.52%
Pain: 4 people, 9.52%
Nausea (feeling of having an urge to vomit): 4 people, 9.52%
Carcinoid Tumor: 4 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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