Jentadueto and Crestor drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Jentadueto (linagliptin; metformin hydrochloride) and Crestor (rosuvastatin calcium). Common drug interactions include diarrhoea among females and cardiac failure among males.
The phase IV clinical study analyzes what interactions people have when they take Jentadueto and Crestor. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.
What is Jentadueto?
Jentadueto has active ingredients of linagliptin; metformin hydrochloride. eHealthMe is studying from 1,319 Jentadueto users. Check the latest studies of Jentadueto.
What is Crestor?
Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,761 Crestor users. Check the latest studies of Crestor.
52 people who take Jentadueto and Crestor together, and have interactions are studied.

What are the common drug interactions of Jentadueto and Crestor, by gender? *:
female:
- Diarrhoea
- Pain
- Abdominal pain upper
- Blood glucose increased
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Psoriasis (immune-mediated disease that affects the skin)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Insomnia (sleeplessness)
- Nausea (feeling of having an urge to vomit)
male:
- Cardiac failure
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Contusion (a type of hematoma of tissue in which capillaries)
- Coronary artery stenosis (narrowing of coronary artery)
- Cough
- Dizziness
- Drug hypersensitivity
- Fatigue (feeling of tiredness)
- Heart rate increased
- Hyperglycaemia (high blood sugar)
What are the common drug interactions of Jentadueto and Crestor, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
50-59:
- Abdominal pain upper
- Cardiac failure
- Drug ineffective
- Nausea (feeling of having an urge to vomit)
- Blood glucose increased
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Impaired work ability
60+:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Cardiac failure
- Abdominal pain
- Cataract (clouding of the lens inside the eye)
- Diarrhoea
- Dyspepsia (indigestion)
- Feeling cold
- Pain
- Vomiting
- Vulvovaginal pain
What are the existing conditions these people have? *
- Type 2 Diabetes: 14 people, 26.92%
- High Blood Pressure: 12 people, 23.08%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 7 people, 13.46%
- Diabetes: 7 people, 13.46%
- Psoriasis (immune-mediated disease that affects the skin): 4 people, 7.69%
- Stable Angina (a constant chest pain): 3 people, 5.77%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.77%
- Acute Myocardial Infarction (acute heart attack): 3 people, 5.77%
* Approximation only. Some reports may have incomplete information.
Do you take Jentadueto and Crestor?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Jentadueto (1,319 reports)
- Crestor (149,761 reports)
Browse all drug interactions of Jentadueto and Crestor:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Jentadueto:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Crestor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Jentadueto and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Crestor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on linagliptin; metformin hydrochloride and rosuvastatin calcium (the active ingredients of Jentadueto and Crestor, respectively), and Jentadueto and Crestor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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