Juxtapid and Humalog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Juxtapid (lomitapide mesylate) and Humalog (insulin lispro recombinant). Common drug interactions include diarrhoea among females and blood glucose decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Juxtapid and Humalog. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Juxtapid?

Juxtapid has active ingredients of lomitapide mesylate. eHealthMe is studying from 4,279 Juxtapid users. Check the latest studies of Juxtapid.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

30 people who take Juxtapid and Humalog together, and have interactions are studied.

What are the common drug interactions of Juxtapid and Humalog, by gender? *:

female:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Weight increased
Abdominal distension
Blood cholesterol increased
Blood glucose increased
Constipation
Dyspepsia (indigestion)
Flatulence (flatus expelled through the anus)
Stress

male:

Blood glucose decreased
Diarrhoea
Vomiting
Abdominal pain upper
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypoglycaemic unconsciousness (unconsciousness due to low blood sugar)
Malaise (a feeling of general discomfort or uneasiness)
Bowel movement irregularity
Defaecation urgency (a sudden compelling urge to defecate)
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Juxtapid and Humalog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood glucose decreased
Bowel movement irregularity
Defaecation urgency (a sudden compelling urge to defecate)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Vomiting

50-59:

Abdominal distension
Dyspepsia (indigestion)
Flatulence (flatus expelled through the anus)
Nausea (feeling of having an urge to vomit)
Abasia (inability to walk)
Anxiety disorder
Blood glucose decreased
Cardiac failure congestive
Chest pain
Depression

60+:

Diarrhoea
Blood cholesterol increased
Back pain
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Lip swelling
Pain
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)
Pharyngitis (inflammation of the pharynx, causing a sore throat)

What are the existing conditions these people have? *

Type 2 Diabetes: 4 people, 13.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 13.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 13.33%
High Blood Pressure: 4 people, 13.33%
Depression: 4 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.00%
Sinusitis (inflammation of sinus): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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