Kadcyla and Furosemide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Kadcyla (ado-trastuzumab emtansine) and Furosemide (furosemide). Common drug interactions include lacrimation increased among females and abasia among males.
The phase IV clinical study analyzes what interactions people have when they take Kadcyla and Furosemide. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.
What is Kadcyla?
Kadcyla has active ingredients of ado-trastuzumab emtansine. eHealthMe is studying from 5,813 Kadcyla users. Check the latest studies of Kadcyla.
What is Furosemide?
Furosemide has active ingredients of furosemide. It is often used in fluid retention. eHealthMe is studying from 316,095 Furosemide users. Check the latest studies of Furosemide.
63 people who take Kadcyla and Furosemide together, and have interactions are studied.

What are the common drug interactions of Kadcyla and Furosemide, by gender? *:
female:
- Lacrimation increased
- Platelet count decreased
- Pneumonia
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Pulmonary oedema (fluid accumulation in the lungs)
- Rash pustular (redness with pustules)
- Thrombocytopenia (decrease of platelets in blood)
- Fatigue (feeling of tiredness)
- Pleural effusion (water on the lungs)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
male:
- Abasia (inability to walk)
- Acute leukaemia (blood cancer)
- Hypotension (abnormally low blood pressure)
- Loss of consciousness
- Neuropathy peripheral (surface nerve damage)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Urinary tract infection
- Thrombocytopenia (decrease of platelets in blood)
- Chills (felling of cold)
- Constipation
What are the common drug interactions of Kadcyla and Furosemide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- White blood cell count decreased
- Hemianopia (blindness or reduction in vision in one half of the visual field due to damage of the optic pathways in the brain)
- Nausea (feeling of having an urge to vomit)
- Skin fissures (a crack in the skin)
- Thrombocytopenia (decrease of platelets in blood)
- Cerebral disorder (brain disease)
- Hepatic neoplasm (liver tumour)
- Neuropathy peripheral (surface nerve damage)
- Respiratory failure (inadequate gas exchange by the respiratory system)
40-49:
- Interstitial lung disease
- Thrombocytopenia (decrease of platelets in blood)
- Breast cancer
- Iiird nerve paralysis (totally closed eyelid and a down and out deviation of the eye)
- Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
- Metastases to central nervous system (cancer spreads to central nervous system)
- Metastases to liver (cancer spreads to liver)
- Metastases to meninges (cancer spreads to meninges)
- Nausea (feeling of having an urge to vomit)
- Platelet count decreased
50-59:
- Neuropathy peripheral (surface nerve damage)
- Neutropenia (an abnormally low number of neutrophils)
- Oedema peripheral (superficial swelling)
- Onycholysis (detachment of the nail from the nail bed)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
- Rhinorrhoea (watery mucus discharge from the nose)
- Thrombocytopenia (decrease of platelets in blood)
- Ascites (accumulation of fluid in the abdominal cavity)
- Aspartate aminotransferase increased
- Blood albumin decreased
60+:
- Thrombocytopenia (decrease of platelets in blood)
- Fatigue (feeling of tiredness)
- Pleural effusion (water on the lungs)
- C-reactive protein increased
- Headache (pain in head)
- Restlessness (not able to rest)
- Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Nasal mucosal disorder (disease of mucous membrane)
- Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
What are the existing conditions these people have? *
- Breast Cancer Metastatic: 27 people, 42.86%
- Breast Cancer: 17 people, 26.98%
- Nausea (feeling of having an urge to vomit): 8 people, 12.70%
- Dyspnea (difficult or laboured breathing): 6 people, 9.52%
- Skin Fissures (a crack in the skin): 5 people, 7.94%
- Paronychia (infection in the tissues adjacent to a nail on a finger or toe): 5 people, 7.94%
- Hypertensive Crisis: 5 people, 7.94%
- Gastrointestinal Disorder (functional problems of gastrointestinal tract): 5 people, 7.94%
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 5 people, 7.94%
- Cough: 5 people, 7.94%
* Approximation only. Some reports may have incomplete information.
Do you take Kadcyla and Furosemide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Kadcyla (5,813 reports)
- Furosemide (316,095 reports)
Browse all drug interactions of Kadcyla and Furosemide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Kadcyla:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Furosemide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Kadcyla and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Furosemide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
- Ochoa PS, Fisher T, "A 7‐Year Case of Furosemide‐Induced Immune Thrombocytopenia", Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2013 Jul .
How the study uses the data?
The study uses data from the FDA. It is based on ado-trastuzumab emtansine and furosemide (the active ingredients of Kadcyla and Furosemide, respectively), and Kadcyla and Furosemide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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