Kaletra and Azelastine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kaletra (lopinavir; ritonavir) and Azelastine (azelastine hydrochloride). Common drug interactions include anhedonia among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Kaletra and Azelastine. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Kaletra?

Kaletra has active ingredients of lopinavir; ritonavir. It is often used in hiv infection. eHealthMe is studying from 23,070 Kaletra users. Check the latest studies of Kaletra.

What is Azelastine?

Azelastine has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 17,400 Azelastine users. Check the latest studies of Azelastine.

On Jul, 12, 2026

16 people who take Kaletra and Azelastine together, and have interactions are studied.

Kaletra and Azelastine drug interactions.

What are the common drug interactions of Kaletra and Azelastine, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Pain
Osteoporosis (bones weak and more likely to break)
Anxiety
Foot fracture
Bone density decreased
Chronic kidney disease
Arthralgia (joint pain)
Multiple fractures

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Gait disturbance
Mobility decreased (ability to move is reduced)
Osteopenia (a condition where bone mineral density is lower than normal)
Upper limb fracture
Back pain
Blood creatinine increased
Decreased activity
Drug ineffective

What are the common drug interactions of Kaletra and Azelastine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Foot fracture
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Chronic kidney disease
Blood creatinine increased
Renal impairment (severely reduced kidney function)
Bone density decreased
Decreased activity

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Osteoporosis (bones weak and more likely to break)
Pain
Bone density decreased
Chronic kidney disease
Anxiety
Foot fracture
Osteopenia (a condition where bone mineral density is lower than normal)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Dysstasia (difficulty in standing)
Fall
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Emotional distress
Lower limb fracture
Multiple fractures
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)

What are the existing conditions these people have? *

Hiv Infection: 15 people, 93.75%
Asthma: 5 people, 31.25%
Depression: 5 people, 31.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 31.25%
High Blood Cholesterol: 5 people, 31.25%
Stress And Anxiety: 5 people, 31.25%
Hypersensitivity: 5 people, 31.25%
Inflammation: 4 people, 25.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 25.00%
Viral Infection: 4 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Kaletra and Azelastine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously