Relpax and Duragesic-100 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Relpax (eletriptan hydrobromide) and Duragesic-100 (fentanyl). Common drug interactions include depression among females.

The phase IV clinical study analyzes what interactions people have when they take Relpax and Duragesic-100. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Relpax?

Relpax has active ingredients of eletriptan hydrobromide. It is often used in migraine. eHealthMe is studying from 9,259 Relpax users. Check the latest studies of Relpax.

What is Duragesic-100?

Duragesic-100 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 19,509 Duragesic-100 users. Check the latest studies of Duragesic-100.

On Jul, 12, 2026

16 people who take Relpax and Duragesic-100 together, and have interactions are studied.

Relpax and Duragesic-100 drug interactions.

What are the common drug interactions of Relpax and Duragesic-100, by gender? *:

female:

Depression
Restless legs syndrome (a powerful urge to move your legs)
Blood cholesterol increased
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Mood swings (an extreme or rapid change in mood)
Bladder pain
Bladder spasm
Cystitis (inflammation of the wall of the bladder)
Hyperhidrosis (abnormally increased sweating)
Neuralgia (pain in one or more nerves)

male:

n/a

What are the common drug interactions of Relpax and Duragesic-100, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Thrombosis (formation of a blood clot inside a blood vessel)

30-39:

Application site dermatitis
Application site erythema (redness of the skin at application site)
Dehydration (dryness resulting from the removal of water)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Vomiting

40-49:

Aphagia (inability or refusal to swallow)
Irritability
Somnolence (a state of near-sleep, a strong desire for sleep)
Hypersomnia (excessive daytime sleepiness (eds))
Sinusitis (inflammation of sinus)

50-59:

Bladder disorder
Bladder pain
Abdominal discomfort
Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
Breast disorder
Dental caries
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Eating disorder
Fibromyalgia (a long-term condition which causes pain all over the body)
Fluid intake reduced

60+:

n/a

What are the existing conditions these people have? *

Stress And Anxiety: 9 people, 56.25%
Muscle Spasms (muscle contraction): 7 people, 43.75%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 37.50%
High Blood Cholesterol: 6 people, 37.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 37.50%
Breakthrough Pain: 6 people, 37.50%
Nausea (feeling of having an urge to vomit): 4 people, 25.00%
Back Pain: 3 people, 18.75%
Fatigue (feeling of tiredness): 3 people, 18.75%
Depression: 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

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