Kayexalate and Potassium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kayexalate (sodium polystyrene sulfonate) and Potassium (potassium). Common drug interactions include bone disorder among females and face oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Kayexalate and Potassium. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Kayexalate?

Kayexalate has active ingredients of sodium polystyrene sulfonate. eHealthMe is studying from 5,004 Kayexalate users. Check the latest studies of Kayexalate.

What is Potassium?

Potassium has active ingredients of potassium. It is often used in hypokalemia. eHealthMe is studying from 59,147 Potassium users. Check the latest studies of Potassium.

On Jul, 19, 2026

46 people who take Kayexalate and Potassium together, and have interactions are studied.

Kayexalate and Potassium drug interactions.

What are the common drug interactions of Kayexalate and Potassium, by gender? *:

female:

Bone disorder
Neuropathy peripheral (surface nerve damage)
Osteomyelitis (infection of bone)
Pain
General physical health deterioration (weak health status)
Hyperkalaemia (damage to or disease of the kidney)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Diarrhoea
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)

male:

Face oedema (swelling of face)
Hyperthermia (body temperature greatly above normal)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Pancreatitis chronic (chronic inflammation of pancreas)
Pulmonary arterial pressure increased
Sepsis (a severe blood infection that can lead to organ failure and death)
Weight decreased
Abscess neck (neck abscesses)
Addison's disease (addison's disease, a hormonal disorder disease)

What are the common drug interactions of Kayexalate and Potassium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Respiratory failure (inadequate gas exchange by the respiratory system)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Gastritis haemorrhagic (inflammation of stomach with bleeding)

30-39:

Hyperkalaemia (damage to or disease of the kidney)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Abdominal pain
Diarrhoea
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Epistaxis (bleed from the nose)
Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells)
General physical health deterioration (weak health status)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

40-49:

Hyperthermia (body temperature greatly above normal)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Oedema peripheral (superficial swelling)
Pulmonary embolism (blockage of the main artery of the lung)
Vitamin a deficiency
Vitamin d deficiency
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Face oedema (swelling of face)

50-59:

Abscess limb (limb infection)
Bone disorder
Neuropathy peripheral (surface nerve damage)
Osteomyelitis (infection of bone)
Pain
Anaemia (lack of blood)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Pancreatitis chronic (chronic inflammation of pancreas)
Pulmonary arterial pressure increased
Device related infection

60+:

Urinary tract infection
Sepsis (a severe blood infection that can lead to organ failure and death)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Weight decreased
Anaemia (lack of blood)
Abscess neck (neck abscesses)
Addison's disease (addison's disease, a hormonal disorder disease)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia of chronic disease
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)

What are the existing conditions these people have? *

Hyperkalemia (damage to or disease of the kidney): 32 people, 69.57%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 30 people, 65.22%
Sepsis (a severe blood infection that can lead to organ failure and death): 25 people, 54.35%
Depression: 24 people, 52.17%
Insomnia (sleeplessness): 23 people, 50.00%
Urinary Tract Infection: 16 people, 34.78%
Osteoporosis (bones weak and more likely to break): 15 people, 32.61%
Infection: 15 people, 32.61%
Anaemia (lack of blood): 13 people, 28.26%
Fever: 12 people, 26.09%

* Approximation only. Some reports may have incomplete information.

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