Kayexalate and Tracleer drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kayexalate (sodium polystyrene sulfonate) and Tracleer (bosentan). Common drug interactions include fall among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Kayexalate and Tracleer. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Kayexalate?

Kayexalate has active ingredients of sodium polystyrene sulfonate. eHealthMe is studying from 5,004 Kayexalate users. Check the latest studies of Kayexalate.

What is Tracleer?

Tracleer has active ingredients of bosentan. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,125 Tracleer users. Check the latest studies of Tracleer.

On Jul, 17, 2026

17 people who take Kayexalate and Tracleer together, and have interactions are studied.

Kayexalate and Tracleer drug interactions.

What are the common drug interactions of Kayexalate and Tracleer, by gender? *:

female:

Fall
Hepatic failure (liver failure)
Cardiac failure
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Overdose
Right ventricular failure (right half of the heart fails to work)
Septic shock (shock due to blood infection)
Somnolence (a state of near-sleep, a strong desire for sleep)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Anaesthetic complication

male:

Asthenia (weakness)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Dizziness
Hypotension (abnormally low blood pressure)
Fatigue (feeling of tiredness)
Pneumonia
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the common drug interactions of Kayexalate and Tracleer, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acute psychosis (period of mentally unstable behaviour)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Blood calcium decreased
Blood glucose decreased
Blood potassium decreased
Blood sodium decreased
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Delusion (a false belief or opinion)
Depressed level of consciousness
Depression

50-59:

Infection
Renal failure (kidney dysfunction)
Asthenia (weakness)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Dizziness
Hypotension (abnormally low blood pressure)

60+:

Fall
Pulmonary hypertension (increase in blood pressure in the lung artery)
Blood parathyroid hormone increased
Blood pressure systolic decreased
Chest pain
Cytolytic hepatitis (dissolution or destruction of a liver cell)
Femur fracture
Headache (pain in head)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Oxygen saturation decreased

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 6 people, 35.29%
Anaemia (lack of blood): 3 people, 17.65%
Insomnia (sleeplessness): 3 people, 17.65%
High Blood Pressure: 3 people, 17.65%
Osteoporosis (bones weak and more likely to break): 2 people, 11.76%
Drug Eruption (adverse drug reaction of the skin): 2 people, 11.76%
Localised Infection (infection at the single location): 2 people, 11.76%
Iron Deficiency Anaemia: 2 people, 11.76%
Skin Ulcer: 2 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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