Keflex and Aldomet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keflex (cephalexin) and Aldomet (methyldopa). Common drug interactions include depression among females and pulmonary artery stenosis congenital among males.

The phase IV clinical study analyzes what interactions people have when they take Keflex and Aldomet. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

What is Aldomet?

Aldomet has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 2,356 Aldomet users. Check the latest studies of Aldomet.

On Aug, 13, 2026

11 people who take Keflex and Aldomet together, and have interactions are studied.

What are the common drug interactions of Keflex and Aldomet, by gender? *:

female:

Depression
Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Palpitations (feelings or sensations that your heart is pounding or racing)
Activities of daily living impaired
Agitation (state of anxiety or nervous excitement)
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Aortic valve incompetence

male:

Pulmonary artery stenosis congenital (congenital -narrowing (stenosis) that occurs in the lung artery)
Pericardial effusion (fluid around the heart)
Bradycardia (abnormally slow heart action)
Deafness
Urinary retention (the inability to completely or partially empty the bladder)

What are the common drug interactions of Keflex and Aldomet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cough
Dyspnoea (difficult or laboured respiration)

20-29:

n/a

30-39:

n/a

40-49:

Postmenopausal haemorrhage (post-menopausal bleeding)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Rales (an abnormal respiratory sound characterized by fine crackles)
Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease)
Restlessness (not able to rest)
Sinus arrhythmia (a naturally occurring variation in heart rate that occurs during a breathing cycle)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Sinusitis (inflammation of sinus)
Skin ulcer
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

50-59:

n/a

60+:

Drug hypersensitivity
Abdominal pain upper
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deafness
Decreased activity
Depression
Diabetic vascular disorder (diseases of the blood vessels due to diabetes)
Dizziness
Dysaesthesia (abnormal sensation)
Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

Urinary Tract Infection: 4 people, 36.36%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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