Keflex and Astepro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Keflex (cephalexin) and Astepro (azelastine hydrochloride). Common drug interactions include arthropathy among females and deep vein thrombosis among males.
The phase IV clinical study analyzes what interactions people have when they take Keflex and Astepro. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Keflex?
Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.
What is Astepro?
Astepro has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 3,336 Astepro users. Check the latest studies of Astepro.
12 people who take Keflex and Astepro together, and have interactions are studied.

What are the common drug interactions of Keflex and Astepro, by gender? *:
female:
- Arthropathy
- Chest pain
- Swelling
- Hemiplegia (paralysis of one side of the body)
- Inflammation
- Migraine (headache)
- Abdominal pain upper
- Anxiety
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
male:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Peripheral swelling
- Constipation
- Death
- Fall
- Hallucination (an experience involving the perception of something not present)
- Heart rate increased
- Hip fracture
- Lower respiratory tract infection
- Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
What are the common drug interactions of Keflex and Astepro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain upper
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Gallbladder disorder
30-39:
n/a
40-49:
n/a
50-59:
- Inflammation
- Migraine (headache)
- Hemiplegia (paralysis of one side of the body)
60+:
- Constipation
- Death
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Fall
- Hallucination (an experience involving the perception of something not present)
- Herpes zoster
- Hip fracture
- Lower respiratory tract infection
- Peripheral swelling
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 50.00%
- Wheezing (a high-pitched whistling sound made while you breath): 3 people, 25.00%
- Salivary Hypersecretion (excess saliva secretion): 2 people, 16.67%
- Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1 person, 8.33%
- Immunodeficiency Common Variable: 1 person, 8.33%
- Herpes Virus Infection: 1 person, 8.33%
- Hallucinations (sensations that appear real but are created by your mind): 1 person, 8.33%
- Drowsiness: 1 person, 8.33%
- Dementia With Lewy Bodies (progressive degenerative disease or syndrome of the brain): 1 person, 8.33%
- Delusion (a false belief or opinion): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Keflex and Astepro?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Keflex and Astepro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Keflex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Astepro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Keflex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Astepro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on cephalexin and azelastine hydrochloride (the active ingredients of Keflex and Astepro, respectively), and Keflex and Astepro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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