Keflex and Leukine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keflex (cephalexin) and Leukine (sargramostim). Common drug interactions include amnesia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Keflex and Leukine. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

What is Leukine?

Leukine has active ingredients of sargramostim. eHealthMe is studying from 2,188 Leukine users. Check the latest studies of Leukine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

20 people who take Keflex and Leukine together, and have interactions are studied.

What are the common drug interactions of Keflex and Leukine, by gender? *:

female:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Disability
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dysarthria (speech disorder)
Dyspnoea (difficult or laboured respiration)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Impaired healing
Injury

male:

Anxiety
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Sinusitis (inflammation of sinus)
Toothache (tooth pain)
Osteonecrosis of jaw (death of bone of jaw)
Lymphadenopathy (disease or enlargement of lymph nodes)
Osteomyelitis (infection of bone)
Spinal haemangioma (an abnormal, but non cancer blood vessel tumour that commonly occurs in the spine)
Hypertension (high blood pressure)
Aphasia (damage to the parts of the brain that control language)

What are the common drug interactions of Keflex and Leukine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal distension
Abdominal pain upper
Abscess jaw (tooth abscess or root abscess)
Actinomycosis (infection that causes sores, or abscesses)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia of chronic disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)

20-29:

n/a

30-39:

n/a

40-49:

Pain
Abdominal discomfort
Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Aphasia (damage to the parts of the brain that control language)
Back pain

50-59:

n/a

60+:

Anxiety
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Sinusitis (inflammation of sinus)
Toothache (tooth pain)
Osteonecrosis of jaw (death of bone of jaw)
Lymphadenopathy (disease or enlargement of lymph nodes)
Osteomyelitis (infection of bone)
Spinal haemangioma (an abnormal, but non cancer blood vessel tumour that commonly occurs in the spine)
Hypertension (high blood pressure)
Aphasia (damage to the parts of the brain that control language)

What are the existing conditions these people have? *

Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 7 people, 35.00%
Gynecomastia (enlargement of the gland tissue of the male breast): 7 people, 35.00%
Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 25.00%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 5.00%
Pain In Extremity: 1 person, 5.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%
Depression: 1 person, 5.00%
Breast Cancer Stage Iv: 1 person, 5.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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