Keflex and Pregabalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keflex (cephalexin) and Pregabalin (pregabalin). Common drug interactions include oedema among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Keflex and Pregabalin. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,069 Pregabalin users. Check the latest studies of Pregabalin.

On Jul, 12, 2026

59 people who take Keflex and Pregabalin together, and have interactions are studied.

Keflex and Pregabalin drug interactions.

What are the common drug interactions of Keflex and Pregabalin, by gender? *:

female:

Oedema (fluid collection in tissue)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Peripheral swelling
Rash
Swelling
Abdominal distension
Alveolar osteitis (complication of wound healing following extraction of a tooth)
Anaemia (lack of blood)
Animal scratch
Balance disorder

male:

Asthenia (weakness)
Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
Presyncope
Thrombosis (formation of a blood clot inside a blood vessel)
Central nervous system haemorrhage (bleeding in brain and surrounding)
Spinal column stenosis (narrowing of spinal column)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Adverse drug reaction
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)

What are the common drug interactions of Keflex and Pregabalin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia
Alanine aminotransferase increased
Burning sensation
Cataract subcapsular (cataracts that affect the back of the lens)
Cystoid macular oedema (fluid accumulation after cataract surgery)
Diabetes mellitus inadequate control
Diabetic retinal oedema (excessive build-up of fluid in the retina due to diabetes)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dizziness

50-59:

Calcium ionised increased
Candiduria (candida in urine)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Graft thrombosis (clotting at graft)
Haemorrhage (bleeding)
Heparin-induced thrombocytopenia
Hypotension (abnormally low blood pressure)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Memory impairment

60+:

Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Arthralgia (joint pain)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Chills (felling of cold)
Decreased appetite
Ear pain
Erythema (redness of the skin)
Fall

What are the existing conditions these people have? *

Pain: 13 people, 22.03%
Stress And Anxiety: 7 people, 11.86%
High Blood Cholesterol: 7 people, 11.86%
Multiple Myeloma (cancer of the plasma cells): 7 people, 11.86%
Insomnia (sleeplessness): 7 people, 11.86%
Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 10.17%
Asthma: 6 people, 10.17%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 10.17%
Peripheral Sensory Neuropathy (damage to one or more of your peripheral nerves): 5 people, 8.47%
Neuropathy Peripheral (surface nerve damage): 5 people, 8.47%

* Approximation only. Some reports may have incomplete information.

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