Kemadrin and Diazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Kemadrin (procyclidine hydrochloride) and Diazepam (diazepam). Common drug interactions include emotional disorder among females and arrhythmia among males.
The phase IV clinical study analyzes what interactions people have when they take Kemadrin and Diazepam. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.
What is Kemadrin?
Kemadrin has active ingredients of procyclidine hydrochloride. eHealthMe is studying from 503 Kemadrin users. Check the latest studies of Kemadrin.
What is Diazepam?
Diazepam has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 108,384 Diazepam users. Check the latest studies of Diazepam.
31 people who take Kemadrin and Diazepam together, and have interactions are studied.

What are the common drug interactions of Kemadrin and Diazepam, by gender? *:
female:
- Emotional disorder
- Fatigue (feeling of tiredness)
- Feeling jittery
- Feeling of despair
- Gait disturbance
- Gastric ph decreased
- H1n1 influenza (flu (influenza), which is caused by virus influenza a (h1n1))
- Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
- Headache (pain in head)
- Heart rate increased
male:
- Arrhythmia (irregular heartbeat)
- Confusional state
- General physical health deterioration (weak health status)
- Hospitalisation
- Ketoacidosis (high concentrations of ketone bodies in blood)
- Parkinson's disease
- Road traffic accident
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Sudden cardiac death
- Tongue disorder (disease of tongue)
What are the common drug interactions of Kemadrin and Diazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Priapism (prolonged and painful erection that can last from several hours up to a few days)
30-39:
- Contusion (a type of hematoma of tissue in which capillaries)
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Diarrhoea
- Dizziness
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Eye pain
- Feeling of body temperature change
- Hyperhidrosis (abnormally increased sweating)
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Muscle rigidity (muscle stiffness)
40-49:
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Abnormal dreams
- Abortion spontaneous (naturally occurring miscarriage)
- Adverse event
- Aggression
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Arrhythmia (irregular heartbeat)
- Arthralgia (joint pain)
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
- Balance disorder
50-59:
- Arrhythmia (irregular heartbeat)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Loss of consciousness
- Agitation (state of anxiety or nervous excitement)
- Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
- Blood phosphate increased
- Bruxism (habitual grinding of the teeth, typically during sleep)
- Cerebral atrophy (decrement in size of brain)
- Confusion
- Confusional state
60+:
- Accident
- Blood osmolarity increased
- Confusional state
- On and off phenomenon
- Blood urea increased
- General physical health deterioration (weak health status)
- Hospitalisation
- Hypertension (high blood pressure)
- Muscle rigidity (muscle stiffness)
- Parkinson's disease
What are the existing conditions these people have? *
- Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 4 people, 12.90%
- Sedation: 3 people, 9.68%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 9.68%
- Psychotic Disorder: 3 people, 9.68%
- Post-Traumatic Stress Disorder: 3 people, 9.68%
- Parosmia (distortion of the sense of smell, as in smelling odours that are not present): 3 people, 9.68%
- Pain: 3 people, 9.68%
- Oculogyric Crisis (a spasmodic movement of the eyeballs into a fixed position due to medicine reaction): 3 people, 9.68%
- Neuralgia (pain in one or more nerves): 3 people, 9.68%
- Muscle Spasms (muscle contraction): 3 people, 9.68%
* Approximation only. Some reports may have incomplete information.
Do you take Kemadrin and Diazepam?
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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Kemadrin and Diazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Kemadrin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Diazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Kemadrin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on procyclidine hydrochloride and diazepam (the active ingredients of Kemadrin and Diazepam, respectively), and Kemadrin and Diazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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