Kenalog and Sotret drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kenalog (triamcinolone acetonide) and Sotret (isotretinoin). Common drug interactions include anorectal discomfort among females and pruritus among males.

The phase IV clinical study analyzes what interactions people have when they take Kenalog and Sotret. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Kenalog?

Kenalog has active ingredients of triamcinolone acetonide. It is often used in pain. eHealthMe is studying from 10,692 Kenalog users. Check the latest studies of Kenalog.

What is Sotret?

Sotret has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 9,023 Sotret users. Check the latest studies of Sotret.



On Jul, 10, 2026

14 people who take Kenalog and Sotret together, and have interactions are studied.

Kenalog and Sotret drug interactions.

What are the common drug interactions of Kenalog and Sotret, by gender? *:

female:

  1. Anorectal discomfort
  2. Blood pressure increased
  3. Cyst (a closed sac)
  4. Dermoid cyst (an abnormal growth (teratoma) containing epidermis, hair follicles, and sebaceous glands)
  5. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  6. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  7. Drug hypersensitivity
  8. Drug ineffective
  9. Dry eye (lack of adequate tears)
  10. Dry mouth

male:

  1. Pruritus (severe itching of the skin)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  4. Sacroiliitis (an inflammation of the sacroiliac joint)
  5. Small intestinal obstruction (blockage in small intestine)
  6. Emotional distress
  7. Pouchitis (inflammatory bowel disease)
  8. Renal disorder (kidney disease)
  9. Dehydration (dryness resulting from the removal of water)
  10. Device related infection

What are the common drug interactions of Kenalog and Sotret, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Back pain
  3. Colitis ulcerative (inflammation of colon with ulcer)
  4. Epistaxis (bleed from the nose)
  5. Ileus (a painful obstruction of the ileum or other part of the intestine)
  6. Inflammatory bowel disease
  7. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  8. Neck injury
  9. Pelvic abscess
  10. Pruritus (severe itching of the skin)

20-29:

  1. Alopecia (absence of hair from areas of the body)
  2. Psoriasis (immune-mediated disease that affects the skin)
  3. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  4. Skin haemorrhage (bleeding into skin)
  5. Skin lesion
  6. Arthralgia (joint pain)
  7. Balance disorder
  8. Hidradenitis (chronic disease of a type of sweat gland)
  9. Lymphadenopathy (disease or enlargement of lymph nodes)
  10. Migraine (headache)

30-39:

n/a

40-49:

  1. Dermal cyst

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Hidradenitis (chronic disease of a type of sweat gland): 5 people, 35.71%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 14.29%
  3. Drowsiness: 2 people, 14.29%
  4. Depression: 2 people, 14.29%
  5. Constipation: 2 people, 14.29%
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Kenalog and Sotret:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Kenalog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sotret:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kenalog and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sotret and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on triamcinolone acetonide and isotretinoin (the active ingredients of Kenalog and Sotret, respectively), and Kenalog and Sotret (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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