Keppra xr and Adderall drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Keppra xr (levetiracetam) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include vomiting among females and amnesia among males.
The phase IV clinical study analyzes what interactions people have when they take Keppra xr and Adderall. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Keppra xr?
Keppra xr has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 2,272 Keppra xr users. Check the latest studies of Keppra xr.
What is Adderall?
Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,226 Adderall users. Check the latest studies of Adderall.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
17 people who take Keppra xr and Adderall together, and have interactions are studied.

What are the common drug interactions of Keppra Xr and Adderall, by gender? *:
female:
- Vomiting
- Alopecia (absence of hair from areas of the body)
- Breast cancer metastatic
- Decreased appetite
- Disability
- Drug ineffective
- Dry eye (lack of adequate tears)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Insomnia (sleeplessness)
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
male:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Concussion (short loss of normal brain function in response to a head injury)
- Craniocerebral injury (injury to cranium and brain)
- Exposure to toxic agent
- Decreased appetite
- Partial seizures (seizures which affect only a part of the brain at onset)
- Poor quality sleep
- Road traffic accident
- Stress
- Toxic shock syndrome (a rare but serious medical condition caused by a bacterial infection)
What are the common drug interactions of Keppra Xr and Adderall, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Dry eye (lack of adequate tears)
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Insomnia (sleeplessness)
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
- Memory impairment
- Nasopharyngitis (inflammation of the nasopharynx)
- Nightmare (unpleasant dream)
- Oral pain
- Panic disorder
- Tremor (trembling or shaking movements in one or more parts of your body)
50-59:
- Hot flush (sudden feelings of heat)
- Pneumonia
- Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
- Streptococcal infection
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 88.24%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 58.82%
- Neck Pain: 4 people, 23.53%
- Drowsiness: 4 people, 23.53%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 17.65%
- Depression: 3 people, 17.65%
- Pain: 2 people, 11.76%
- Neuralgia (pain in one or more nerves): 2 people, 11.76%
- Muscle Spasms (muscle contraction): 2 people, 11.76%
- Stress And Anxiety: 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Keppra xr and Adderall?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Keppra xr and Adderall:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Keppra xr:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Adderall:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Keppra xr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Adderall and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on levetiracetam and amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Keppra xr and Adderall, respectively), and Keppra xr and Adderall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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