Keppra and Elaprase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keppra (levetiracetam) and Elaprase (idursulfase). Common drug interactions include device related infection among females and infusion related reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Keppra and Elaprase. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

What is Elaprase?

Elaprase has active ingredients of idursulfase. eHealthMe is studying from 2,235 Elaprase users. Check the latest studies of Elaprase.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

24 people who take Keppra and Elaprase together, and have interactions are studied.

What are the common drug interactions of Keppra and Elaprase, by gender? *:

female:

Device related infection
Dyspnoea (difficult or laboured respiration)
Increased upper airway secretion
Moraxella infection (bacterial infection)
Staphylococcal infection (an infection with staphylococcus bacteria)

male:

Infusion related reaction
Death
Respiratory failure (inadequate gas exchange by the respiratory system)
Respiratory tract infection
Swelling face
Tachypnoea (a condition of rapid breathing over 20 per minute)
Tremor (trembling or shaking movements in one or more parts of your body)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Urticaria (rash of round, red welts on the skin that itch intensely)
Wheezing (a high-pitched whistling sound made while you breath)

What are the common drug interactions of Keppra and Elaprase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Renal disorder (kidney disease)
Respiratory distress (difficulty in breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)
Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Deafness bilateral
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Otitis media (inflammation of the middle ear)

10-19:

Infusion related reaction
Dyspnoea (difficult or laboured respiration)
Anaphylactic reaction (serious allergic reaction)
Faecal incontinence (a lack of control over passing stool)
Increased upper airway secretion
Swelling face
Tachypnoea (a condition of rapid breathing over 20 per minute)
Tremor (trembling or shaking movements in one or more parts of your body)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Wheezing (a high-pitched whistling sound made while you breath)

20-29:

Death
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Pyrexia (fever)
Waist circumference increased

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 16.67%
Pain: 3 people, 12.50%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 2 people, 8.33%
Essential Hypertension (primary hypertension): 2 people, 8.33%
Burkholderia Pseudomallei Infection (infection caused by group of bacteria burkholderia pseudomallei): 2 people, 8.33%
Burkholderia Mallei Infection (infection caused by group of bacteria burkholderia mallei): 2 people, 8.33%
Agitation (state of anxiety or nervous excitement): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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