Keppra and Nucynta er drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keppra (levetiracetam) and Nucynta er (tapentadol hydrochloride). Common drug interactions include confusional state among females and apraxia among males.

The phase IV clinical study analyzes what interactions people have when they take Keppra and Nucynta er. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

What is Nucynta er?

Nucynta er has active ingredients of tapentadol hydrochloride. It is often used in pain. eHealthMe is studying from 2,508 Nucynta er users. Check the latest studies of Nucynta er.

On Jul, 20, 2026

13 people who take Keppra and Nucynta er together, and have interactions are studied.

Keppra and Nucynta er drug interactions.

What are the common drug interactions of Keppra and Nucynta Er, by gender? *:

female:

Confusional state
Depressed level of consciousness
Depression
Drug ineffective
Dysphonia (speech disorder attributable to a disorder of phonation)
Gait disturbance
Memory impairment
Seasonal allergy (allergic condition due to certain season)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Tooth extraction

male:

Apraxia (disorder that affects a person's ability to organize the movements of the muscles used in speech)
Dysarthria (speech disorder)
Gait disturbance
Hypertensive crisis
Personality change

What are the common drug interactions of Keppra and Nucynta Er, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Confusional state
Depressed level of consciousness
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug hypersensitivity

50-59:

n/a

60+:

Gait disturbance
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Seasonal allergy (allergic condition due to certain season)
Tooth extraction
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Urinary tract infection
Weight decreased
Asthenia (weakness)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Dysstasia (difficulty in standing)

What are the existing conditions these people have? *

Constipation: 6 people, 46.15%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 30.77%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 23.08%
Pain In Extremity: 3 people, 23.08%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 23.08%
Fatigue (feeling of tiredness): 3 people, 23.08%
Flatulence (flatus expelled through the anus): 3 people, 23.08%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 23.08%
Muscle Spasms (muscle contraction): 3 people, 23.08%

* Approximation only. Some reports may have incomplete information.

Do you take Keppra and Nucynta er?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously